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A A Amis

Publications and source records attributed to A A Amis.

At least 19 recordsLinked to original sources

A biomechanical study of four different meniscal repair systems, comparing pull-out strengths and gapping under cyclic loading.

Most studies comparing the biomechanical properties of different meniscal repair systems have simply investigated load to failure. Meniscal tissue is highly anisotropic, and far weaker under tension in the radial direction. Radially oriented loading to failure may not therefore be the most physiologically relevant in vitro test for repair of circumferential tears, and determining gapping across repair sites under cyclical loading at lower loads may be of greater importance. Using bovine menisci, vertical circumferential incisions were repaired using a simple vertical 2-0 PDS suture, Meniscal Arrow, Meniscal Fastener or T-Fix. Repairs were tested by simple loading to failure in a materials testing machine, and by cyclic loading between 5 and 10 N for 25 cycles. Initial gapping across the repairs was measured using a digital micrometer, and the increase in gapping under cyclic loading measured using a Differential Voltage Reluctance Transducer. The mean loads to failure for each of the repair groups were: sutures 72.7 N, Arrows 34.2 N, Fasteners 40.8 N and T-Fix 49.1 N. The load to failure was significantly greater with sutures than with Arrows or Fasteners. The mean gapping across the repairs for each of the repair groups after 25 loading cycles were: sutures 3.29 mm, Arrows 2.18 mm, Fasteners 3.99 mm and T-Fix 3.47 mm. The mean gapping was significantly less with Arrows than with Sutures, Fasteners or T-Fix. These results confirm that meniscal repair by suturing gives the highest load to failure, but show that Arrows give superior hold under lower loads, with the least gapping across repairs under cyclic loading of the four methods tested.

Animals↗

Standardisation of the description of patellofemoral motion and comparison between different techniques.

Patellofemoral motion is significant clinically, yet in the literature many different methods and terminologies are used, thus making comparison between studies difficult. We review and explain the different methods used for the description of patellofemoral joint motion, compare these methods by experimentation, and propose a standardised method. We found three main methods for describing patellar motion: motion of the patella about femoral body fixed axes, about patellar body fixed axes, and a combination of these. Description about femoral body fixed axes does not make sense clinically. Description about patellar body fixed axes is straightforward, yet the definition of these axes is prone to error due to the lack of anatomical landmarks. The combination method makes most sense clinically and uses more easily found anatomical landmarks. Patellar flexion varied by up to 26% when describing the motion about different axes. Tilt and shift were highly sensitive to the choices of coordinate systems and the axes of motion. The pattern of rotation was consistent between all methods; however, differences between the methods increased with patellar flexion. We propose the description of patello-femoral motion in terms of shift (along a femoral medial-lateral axis), tilt (about the patellar long axis), rotation (about a floating patellar anterior-posterior axis) and flexion (about the femoral medial-lateral axis).

Femur↗

Meniscofemoral ligaments revisited. Anatomical study, age correlation and clinical implications.

The meniscofemoral ligaments were studied in 84 fresh-frozen knees from 49 cadavers. Combined anterior and posterior approaches were used to identify the ligaments. In total, 78 specimens (93%) contained at least one meniscofemoral ligament. The anterior meniscofemoral ligament (aMFL) was present in 62 specimens (74%), and the posterior meniscofemoral ligament (pMFL) in 58 (69%). The 42 specimens (50%) in which both ligaments were present were from a significantly younger population than that with one MFL or none (p < 0.05). Several anatomical variations were identified, including oblique fibres of the posterior cruciate ligament (PCL), which were seen in 16 specimens (19%). These were termed the 'false pMFL'. The high incidence of MFLs and their anatomical variations should be borne in mind during arthroscopic and radiological examination of the PCL. It is important to recognise the oblique fibres of the PCL on MRI in order to avoid wrongly identifying them as either a pMFL or a tear of the lateral meniscus. The increased incidence of MFLs in younger donors suggests that they degenerate with age.

Adolescent↗

Intraoperative measurement of knee kinematics in reconstruction of the anterior cruciate ligament.

Our objectives were to establish the envelope of passive movement and to demonstrate the kinematic behaviour of the knee during standard clinical tests before and after reconstruction of the anterior cruciate ligament (ACL). An electromagnetic device was used to measure movement of the joint during surgery. Reconstruction of the ACL significantly reduced the overall envelope of tibial rotation (10 degrees to 90 degrees flexion), moved this envelope into external rotation from 0 degrees to 20 degrees flexion, and reduced the anterior position of the tibial plateau (5 degrees to 30 degrees flexion) (p < 0.05 for all). During the pivot-shift test in early flexion there was progressive anterior tibial subluxation with internal rotation. These subluxations reversed suddenly around a mean position of 36 +/- 9 degrees of flexion of the knee and consisted of an external tibial rotation of 13 +/- 8 degrees combined with a posterior tibial translation of 12 +/- 8 mm. This abnormal movement was abolished after reconstruction of the ACL.

Adult↗

The anatomy of the patellar tendon.

The morphology of the attachment of the patellar tendon, its bundle orientation, the differential fascicles length and the position of the apex of the patella were assessed in 22 cadaveric human knees. The patellar apex was 39+/-6% of the width of the tendon from its medial edge. The bulk of tendon was attached to the distal two-thirds of the anterior aspect of the patella. In six cases tendon fibres originated from the posterior surface of the apex of the patella, forming a ridge on the back of tendon. This may represent an anatomical variant accounting for the increased tendon thickness noted on MRI, both incidentally and during assessment for patellar tendonitis. Fascicles were parallel in the sagittal plane but converged in the frontal plane toward their tibial attachment. When bone-patellar tendon-bone (B-PT-B) grafts were harvested, as for anterior cruciate ligament reconstruction, the grafts narrowed distally. When harvesting B-PT-B, the oblique orientation of the fibres in the coronal plane must be borne in mind.

Aged↗

A comparative study of 'isometric' points for anterior cruciate ligament graft attachment.

Anterior cruciate ligament (ACL) reconstruction depends critically on isometric graft placement. Unfortunately, different supposedly isometric points have been published, and no prior work has compared them to find out which are really isometric. The purpose of this study was to compare the isometry of previously published 'isometric' points for ACL reconstruction. The isometric points and knee loadings of previous studies were reproduced accurately in 12 fresh cadaveric knees. The length changes were measured through 140 degrees knee flexion, using an intra-articular suture attached to a displacement transducer. Six points had less than 1 mm length change and were located proximally in the natural ACL attachment at the posterior end of Blumensaat's line. The other seven points had length change patterns that would cause ACL graft tightening or slackening with knee flexion if they were used as the sites of bone tunnels for graft placement. This study confirms the existence of an isometric zone close to the posterior end of Blumensaat's line under several loading conditions. Other graft attachment points are less suitable for ACL reconstruction.

Aged↗

Periprosthetic bone mineral density changes with femoral components of differing design philosophy.

We measured the bone mineral density in 22 patients with the cylindrical stemmed cobalt-chrome AML prosthesis (collared) and in 22 patients with the tapered stem titanium CLS prosthesis (collarless). DEXA scanning was undertaken at a mean of 40 months in the AML and 52 months in the CLS group from the time of implant insertion. In both groups the greatest mean loss of BMD was found in Gruen zone 7 and the least change in Gruen zone 5. In all zones the BMD loss was greater in the AML group but only statistically significant in zones 6 (P<0.05) and 7 (P<0.01). Although numerous factors affect BMD changes around cementless implants, this study suggests that less bone loss can be associated with the titanium CLS stem.

Absorptiometry, Photon↗

Cranial cruciate stability in the rottweiler and racing greyhound: an in vitro study.

An in vitro biomechanical study of cadaver stifles from rottweilers and racing greyhounds was undertaken to evaluate the contribution of the cranial cruciate ligament to stifle joint stability. This was performed at differing stifle joint angles, first with the joint capsules and ligaments intact and then with all structures removed except for the cranial cruciate ligament. Craniocaudal laxity increased in both breeds as stifle flexion increased. The rottweiler stifle showed greater craniocaudal joint laxity than the racing greyhound at all joint angles between 150 degrees and 110 degrees, but the actual increases in joint laxity between these joint angles were similar for both breeds. Tibial rotation during craniocaudal loading of the stifle increased craniocaudal laxity in both breeds during joint flexion. The relative contribution of the cranial cruciate ligament to cranial stability of the stifle joint increased as the joint flexed and was similar in both breeds.

Animals↗

Comparison of the biomechanical properties of rottweiler and racing greyhound cranial cruciate ligaments.

An in vitro study of rottweiler and racing greyhound cranial cruciate ligaments revealed that the rottweiler ligaments had a significantly greater cross-sectional area at their distal attachments. Mechanical testing showed that the ultimate load related to body mass was significantly higher in the extended racing greyhound stifle during cranial tibial loading to failure, as were linear stiffness, tensile strength and tangent modulus. During ligament axis loading to failure, the only significant difference in structural and mechanical properties recorded between the two breeds was a greater ultimate strain for the greyhound ligament with the stifle joint flexed. Energy absorbed by the ligament complex at failure during cranial tibial loading was twice that for ligament axis loading for both breeds. The clinical significance is that the rottweiler cranial cruciate ligament is more vulnerable to damage as it requires half the load per unit body mass that the greyhound requires to cause a rupture.

Animals↗

Failure mechanisms of polyester fiber anterior cruciate ligament implants: A human retrieval and laboratory study.

It has been hypothesized that ACL implant failure is often caused by bone impingement in knee extension following malplacement of the tibial tunnel. This study examined polyethylene terephtalate fiber ACL implants retrieved from a clinical study, and, to confirm the hypothesis, also set up a laboratory study intended to duplicate the failure mechanism. SEM and TEM examination of 25 ruptured implants gave details of fiber failure morphology, with shearing into longitudinal fibrils, followed by rupture, when the fibrils burst apart. Cadaver joints were run in a knee simulator, with deliberately impinging ACL implants. SEM examination of implants abraded in the knee in vitro showed identical fiber damage patterns, thus confirming the impingement hypothesis.

Anterior Cruciate Ligament↗

Correlation between pre-operative periprosthetic bone density and post-operative bone loss in THA can be explained by strain-adaptive remodelling.

Periprosthetic adaptive bone remodelling after total hip arthroplasty can be simulated in computer models, combining bone remodelling theory with finite element analysis. Patient specific three-dimensional finite element models of retrieved bone specimens from an earlier bone densitometry (DEXA) study were constructed and bone remodelling simulations performed. Results of the simulations were analysed both qualitatively and quantitatively. Patterns of predicted bone loss corresponded very well with the DEXA measurements on the retrievals. The amount of predicted bone loss, measured quantitatively by simulating DEXA on finite element models, was found to be inversely correlated with the initial bone mineral content. It was concluded that the same clinically observed correlation can therefore be explained by mechanically induced remodelling. This finding extends the applicability of numerical pre-clinical testing to the analysis of interaction between implant design and initial state of the bone.

Absorptiometry, Photon↗

Polyester fibre prosthetic anterior cruciate ligament implant rupture: necrosis of ingrown connective tissue.

AIMS: To describe the histopathological and microanalytical features in seven cases of ruptured Apex(R) polyester (Terylene(R)) fibre anterior cruciate ligament prosthesis. METHODS AND RESULTS: Transmitted and polarized light microscopy was performed in all cases; one case was investigated by immunohistochemistry, transmission electron microscopy and scanning electron microscopy, with backscatter and X-ray detectors for elemental microanalysis. For comparison we also studied synovial biopsy material and unused polyester fibres. In the excised ligaments there was much ingrowth of fibrous tissue accompanying a florid giant cell reaction to the individual intact polyester fibres throughout the ligaments. Phagocytosis of particles of prosthesis-derived material was demonstrated and a striking finding was of necrosis of the ingrown connective tissue in the central portions of the ligaments. Hyalinized areas and 'neoligament growth' were less striking. A consistent finding in the polyester fibres was of small particles containing antimony, used as a catalyst in the manufacturing process. CONCLUSIONS: The pattern of reaction to the prosthetic material and the presence of necrosis differ from previous descriptions in animal and human explants of this and other prosthesis types. The mechanical effect of the necrosis is unlikely to be of significance with this ligament, which is load-bearing ab initio.

Adult↗

Incidence and mechanism of the pivot shift. An in vitro study.

The aim of this study was to determine the incidence and mechanism of the pivot shift phenomenon in the normal and anterior cruciate ligament transected knee in vitro. Fifteen knees were tested under a range of valgus moments and iliotibial tract tensions when intact and after anterior cruciate ligament transection. Knee kinematics were measured and described in terms of tibial rotation as the knee flexed. Eight knees pivoted after anterior cruciate ligament transection. The mean pivot shift motion was an external tibial rotation of 17 degrees (+/- 11 degrees standard deviation) over a range of 27 degrees (+/- 24 degrees) knee flexion, at a mean flexion angle of 56 degrees (+/- 27 degrees). Clinically, this corresponds to a reduction of an anteriorly subluxed lateral tibial plateau as the knee flexes. When intact, pivoting and nonpivoting knees had similar anteroposterior laxity, but after anterior cruciate ligament transection, the pivoting group had significantly greater laxity. The loading required to elicit the pivot shift was critical and variable between knees, which raises questions about comparing clinicians' techniques and results in assessing the buckling instability attributable to anterior cruciate ligament injury.

Anterior Cruciate Ligament Injuries↗

Bone adaptation to a polyester fiber anterior cruciate ligament replacement.

A series of polyester fiber ACL implants was studied in ovine stifle joints up to 2 years postimplantation. The implants were linked to the bone-tunnel wall by oriented fibrous tissue. Cross-sections of the tunnels showed bone ingrowth among the implant fibers at 2 years. A human trial of the Apex implant yielded a series of retrievals, some associated with gross bone-tunnel enlargement. There was no evidence of bone ingrowth in the human implants. It was hypothesized that-tunnel enlargement resulted from fretting at the implant-tissue interface in response to cyclic loads in use.

Adaptation, Physiological↗

Quantitative study of the quadriceps muscles and trochlear groove geometry related to instability of the patellofemoral joint.

This was a quantitative study of the major anatomical structures associated with instability of the patellofemoral joint: the quadriceps muscles and the femoral trochlear groove. The attachments of the muscles to the patella, their lines of action, and their relative sizes (physiological cross-sectional areas) were found. On the basis of the physiological cross-sectional areas, it was estimated that the central muscles-the rectus femoris and vastus intermedius-contributed 35% of the quadriceps strength, with 40% from the vastus lateralis and 25% from the vastus medialis. The vastus lateralis had the most variable results, with the ratio of the lateralis to the medialis ranging from 0.90 to 2.18; this may be associated with patellar instability. Both the long and oblique parts of the vastus medialis were more oblique than the corresponding parts of the vastus lateralis. Photographic "skyline" views of the trochlear groove produced data on the sulcus angle and ratio of depth to width. The data showed that the trochlear groove did not deepen in the area contacted by the patella with progressive knee flexion (p > 0.53), contrary to popular belief. These data are useful for objective analysis of patellofemoral stability and related surgical interventions.

Aged↗

Anterior cruciate ligament graft positioning, tensioning and twisting.

This paper reports on a scientific workshop to study anterior cruciate ligament (ACL) reconstruction. The aim is to present recommendations for ACL reconstruction methods that will be of use for surgeons. A study of knee anatomy and graft placement concluded that the tibial attachment must be posterior enough to avoid graft impingement against the femur, and methods to attain this were presented. On the femur, poor graft placement leads to excessive changes of the graft attachment site separation distance as the knee flexes, and the worst case corresponds to the attachment being too far anterior. It was agreed that there were typical patterns of graft tension changes as the knee flexes, and that grafts should be tensioned close to full knee extension. A typical tensioning protocol would be 60 N tension applied at 10 degrees of flexion. It was recognised that graft remodelling caused uncontrollable tension changes post-operation. Graft twisting, to recreate the anatomical spiral of ACL fibres seen in the flexed knee, was also discussed.

Anterior Cruciate Ligament↗

In vitro testing protocols for the cruciate ligaments and ligament reconstructions.

The techniques that have been used to characterize the biomechanical behavior of the knee, cruciate ligaments, and cruciate ligament replacements differ, making comparisons between studies difficult or, at times, impossible. Therefore, it is important to standardize the testing protocols and techniques that describe the biomechanical behavior of the knee and cruciate ligaments. This will allow investigators to express opinions with respect to the interpretation of data, rather than based on differences between testing techniques. Standardized techniques are proposed to locate the origins of the tibial and femoral coordinate systems, and thus, allow comparisons of knee kinematics (e.g., displacements and rotations) between investigations. Standard techniques that can be used to measure the load-displacement behavior of the knee are described, and important considerations that should be appreciated with respect to preparing and testing of the joint are summarized. It is important to evaluate the single cycle load-to-failure characteristics and the cyclic loading response of an anterior cruciate ligament graft, and techniques to evaluate cruciate ligament graft fixation are proposed. The strengths of different models to characterize the biomechanical behavior of the knee are reviewed.

Anterior Cruciate Ligament↗