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Biomedical subjects

A A Fomina

Publications and source records attributed to A A Fomina.

At least 19 recordsLinked to original sources

[Differentiated immunocorrective therapy in nonspecific ulcerative colitis].

A comparative study of the clinico-immunological efficacy of steroid hormones and thymus drugs in 50 patients with unspecific ulcerative colitis of different activity grades revealed that their efficacy was not similar at different phases of the disease and depended on the activity of the inflammatory process. Corticosteroids were more effective in inflammatory-destructive changes in the mucosa of the large intestine while in mild inflammation with prevalence of ulcerative-reparative processes, immunomodulators (thymalin) are preferred.

Adjuvants, Immunologic↗

[Changes in the trace element content of the blood in chronic hepatitis].

Trace elements were examined spectrophotometrically in 45 patients with chronic hepatitis (persisting--31; chronic--14). Lead and cadmium showed a significant increase both in the healthy and hepatitis patients. A reduction of zinc and increase of copper was found in patients with chronic hepatitis. Changes in the content of microelements depended on the severity of the disease.

Adult↗

[The T- and B-immunity systems in patients with digestive organ diseases and exposure to internal radiation].

Results are reported of an immunological examination of 534 patients with digestive diseases and 130 healthy persons. 282 patients subjected to radiation effects showed a marked and persistent T-lymphocytopenia, B-lymphocytosis, reduction of the content of T-helpers, T-suppressors, dysimmunoglobulinemia characterized by reduction of IgG content and excessive IgA secretion. These changes were observed during the period of exacerbation and remission requiring the use of immunocorrective agents.

Accidents↗

[The characteristics of the clinical course of digestive organ diseases in persons subjected to ionizing radiation exposure resulting from the accident at the Chernobyl Atomic Electric Power Station].

Results of a study of 1905 persons are reported. Of them 1775 showed diseases of the digestive organs. Among them were were 275 who were subjected to the effect of ionizing radiation. In these 275 patients the most frequent pathology were erosive lesions of the gastric and duodenal mucosa, gastroesophageal reflux, esophagitis. There was a dependence of the onset of the disease and stay in the disaster Zone. The disease was accompanied by a stable T-cellular immunodeficiency that exacerbated the course of the disease. It is recommended to include immunocorrectors in the complex therapy of these diseases.

Accidents↗