PubMed Health⌕ Search

Biomedical subjects

A A Grosu

Publications and source records attributed to A A Grosu.

At least 19 recordsLinked to original sources
PubMed1991

[Effectiveness and pharmacodynamics of tobanum in patients with paroxysmal reciprocal atrioventricular tachycardia].

The antiarrhythmic effects and pharmacodynamics of tobanum were evaluated in 28 patients wist paroxysms of reciprocal atrioventricular tachycardia, by using transesophageal cardiac pacing. The agent given in a single dose of 10 mg produced antiarrhythmic effects in 70% patients with paroxysms of atrioventricular nodal tachycardia and in 40% with atrioventricular tachycardia in the presence of the Wolff--Parkinson-White syndrome. After administration of the drug, its antiarrhythmic effect occurred on an average 1.5 h and retained for 27 h.

Adolescent↗
PubMed1991

[Possibilities of the combined use of transesophageal electrostimulation of the heart and physical load in the diagnosis of paroxysmal reciprocal atrioventricular tachycardia].

Possibilities of using transesophageal electrostimulation of the heart in combination with a physical load were studied in 38 patients with paroxysms of reciprocal atrioventricular (AV) tachycardia. The study has shown that the physical load exerts a pronounced influence on the induction, persistence, and electrophysiological parameters of AV tachycardia, significantly increases the functional capacity of the anterograde conduction along the anomalous tract, and reduces the efficacy of vagal techniques in alleviating paroxysms of AV tachycardia.

Adult↗
PubMed1990

[Secondary prevention of arterial hypertension in rural population of Moldavia].

The results of the third year of nondrug and pharmacological prevention of arterial hypertension according to the steppedcare scheme of WHO are provided. A low rate of response (46%) to annual check-up was noted among rural residents with arterial hypertension detected by screening which hampers the preventive intervention. During the third year of preventive campaign 9.3 percent of people were covered by regular hypertensive treatment, 20.61 percent--by irregular treatment and 24.4 percent with elevated blood pressures detected by screening never received any treatment. Among women the proportion of those receiving hypertensive treatment (both regular and irregular) was larger. An analysis was made of mean levels of systolic and diastolic blood pressure at the beginning and at the end of the third year of observation in groups of patients with different attitude to treatment. At the third year of implementing the programme of secondary prevention the number of hypertonic patients receiving effective treatment increased 8-fold compared with baseline data. Persons with higher levels of arterial blood pressure were more often applying for treatment. The normalization of arterial blood pressure was noted in 39% of persons applying for regular treatment, 31%--for irregular treatment and in 26% of non-treated hypertonic patients.

Adult↗
PubMed1990

[Functional state of atrioventricular conduction and inducibility of atrioventricular reciprocal tachycardia].

Programmed transesophageal electrical stimulation was used to examine 733 rural inhabitants aged 16 to 70 years. Conduction dissociation along the atrioventricular node was revealed in 65 (8.8%) of the examinees, out of them 12 had induced paroxysms of atrioventricular nodal tachycardia. Atrioventricular tachycardia involving the accessory anomalous pathways was provoked in 10 subjects. Among them 2 had apparent, 1, latent, and 7, obscure forms of the Wolff-Parkinson-White syndrome. The induced paroxysms of atrioventricular tachycardias were sustained in 45.5% of the cases. Only 50% of the subjects had clinical signs of tachycardia in their medical histories.

Adolescent↗
PubMed1990

[The potentials for curing atrial flutter by the combined use of transesophageal electrical stimulation and anti-arrhythmia preparations].

Potentialities of the recovery of the sinus rhythm were studied in 21 patients with atrial flutter (AF) using frequent transesophageal electric cardiac pacing (TEEP) per se and after intravenous injection of ritmilen and novocainamide under outpatient conditions. TEEP made it possible to arrest AF in 24% of patients and to transform flutter into steady atrial fibrillation in 48% of patients. In 28% of cases, the pacing turned out ineffective. Subsequent administration of antiarrhythmic drugs made the rhythm return to normal in 24% of patients, whereas repeated TEEP conducted after drug administration in additionally 33% of patients. The efficacy of frequent TEEP combined with administration of ritmilen and novocainamide amounted to 81%.

Adult↗
PubMed1989

[A comparison of the results of endocardial and transesophageal electrostimulation of the heart in assessing sinus node function and atrioventricular conduction].

Forty five patients with cardiac arrhythmias were included in this study (20 had paroxysmal atrial fibrillation, 19, supraventricular tachycardias; 11 had sick sinus syndrome). In all patients endocardial electrophysiological study and transesophageal atrial pacing were performed in order to study sinus node function and atrioventricular conduction. The results of two methods of investigation have a high correlation. Quantitative criteria were developed for defining normal parameters of sinus node function and atrioventricular conduction during transesophageal atrial pacing.

Adolescent↗
PubMed1989

[The clinical importance of atrial fibrillation-flutter induced by electric transesophageal stimulation of the heart].

A study was made of the clinical importance of atrial fibrillation-flutter (AFF) induced by using different modes of left atrium stimulation via the esophagus. Ninety-eight patients were entered into the study including 40 patients with a history of AFF paroxysms, 24 with risk factors of AFF development, and 27 practically normal persons. The stimulation modes applied permitted reproducing stable paroxysms of AFF in 85 percent of the patients with a history of arrhythmias and in none of the normal persons. As for the patients with risk factors, stable paroxysms of AFF could be induced in 33 percent of the cases. The specificity and sensitivity of transesophageal electrophysiologic stimulation (TEES) with the modes applied were 100 and 82 percent, respectively. The investigations have demonstrated that TEES appeared most effective when applied in the mode of an even increase of the frequency of the set pace up to 300 imp/min.

Adolescent↗