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Biomedical subjects

A A Gunn

Publications and source records attributed to A A Gunn.

At least 19 recordsLinked to original sources
PubMed1991

The acute abdomen: the role of computer-assisted diagnosis.

CAD has been used in over 20,000 patients in an Accident and Emergency Department. Structured documentation has replaced normal case notes and a patient record is created which includes investigations and management. A copy of the documentation acts as an immediate communication to the general practitioner. The information is held on a computer and is readily accessed to produce feedback and to allow audit of any number of parameters. The results show that an improvement in diagnostic accuracy and a reduction in admissions and unnecessary laparotomies continues over 15 years. Problems have occurred; some are inherent to the system and some have been minimized as a result of a series of studies. The savings in terms of finance and facilities are considerable and the cost is small in comparison as the programs are available and the cost of hardware has diminished. It is concluded that documentation is essential. This allows the more accurate collection of information, permits analysis, acts as a method of communication and creates a detailed patient record. The use of this part of the CADA system produces a considerable improvement in the parameters used to assess satisfactory patient management. The computer diagnostic program produces a higher level of diagnostic accuracy than that obtained by doctors who are not using the system. It does not normally exceed the accuracy of the doctors who are using the structured documentation and entering the information into the computer. Other mathematical models might lead to an improvement, particularly if they were based on the diagnostic process used by a senior clinician. The method of entry of information could be facilitated by modern technology, including light pens or word sensitive computers. This would reduce the time required for completion of the documents. A number of possible improvements in the CADA system are reported and some have been studied in detail with little evidence of significant change. The computer part of the system has an educational value and presents a stimulating challenge to the junior hospital staff seeing the patient for the first time in the Accident and Emergency Department. Rapid feedback is possible and advantageous. Possibly the greatest value of the computer is in the analysis of the value of clinical features in diagnosis, which has not been easy in the past. It has also allowed precise assessment of the value of investigations in the diagnosis of patients with a suspected disease, which leads to more appropriate management and the saving of facilities.(ABSTRACT TRUNCATED AT 400 WORDS)

Abdomen, Acute↗
PubMed1989

Acute abdominal pain: the value of liver function tests in suspected cholelithiasis.

Over a 4-year period, prospective data were collected on 311 patients with suspected acute cholecystitis. By identifying the diversity of conditions which can masquerade as acute cholecystitis, we have examined the role of biochemical liver function tests in the diagnosis and management of these patients. The initial clinical diagnosis of acute cholecystitis was confirmed in 229 patients (73.6%). Of those patients on whom liver function tests were performed, 76.3% (206/270) were confirmed to have cholecystitis and 69.9% (144/206) of these had some evidence of liver dysfunction. In the group of patients (64/270) with other diagnoses on whom liver function tests were performed, significantly fewer (57.8%, 37/64) had abnormal liver function tests (P less than 0.05). This is of little clinical value since normal liver function does not exclude cholecystitis (predictive value of negative test = 30.3%). In proven cases of cholecystitis, there was a significantly increased incidence of liver dysfunction when ductal calculi were present. Using the information obtained from this study, an investigative protocol is proposed which may substantially reduce the rate of misdiagnosis of patients with abdominal pain suggestive of cholelithiasis.

Abdomen, Acute↗
PubMed1988

Prediction of choledocholithiasis using a pocket microcomputer.

A computerized method, using a small pocket computer, has been used to predict the presence of choledocholithiasis in a prospective series of 239 patients undergoing cholecystectomy. From an initial data base of 424 patients 36 factors were evaluated and the most important 2 of these were determined by multivariate analysis for use in the prospective analysis. Satisfactory operative cholangiograms were a prerequisite to evaluation of the statistical method and were obtained in 90.4 per cent of cases. Using the computerized method a common bile duct stone would have been overlooked in only 1 patient but 17 unnecessary explorations would have been carried out. The overall accuracy of the computerized method was 92.5 per cent. When the method was applied to a further study of 97 patients from a separate centre the overall accuracy was 85.6 per cent. If the method was used to aid selective use of operative cholangiography, cholangiograms would be performed in 20 per cent and stones would be overlooked in less than 1 per cent.

Cholangiography↗
PubMed1988

Plain abdominal radiographs and acute abdominal pain.

The records of all (5080) patients presenting to a district general hospital with acute abdominal pain over a 4-year period were examined. The contribution of abdominal radiographs to the assessment of patients with suspected appendicitis, urinary tract infection, and non-specific abdominal pain was evaluated, these conditions accounting for 48 per cent of patients with abdominal pain and 32 per cent of those with abdominal radiographs. Any positive information from these radiographs was less likely to be helpful than incidental or inconsistent (and hence potentially misleading). Because of this high 'false positive' rate it is suggested that if the initial diagnosis is suspected appendicitis, urinary tract infection, or non-specific abdominal pain, there is little value in the routine use of abdominal radiographs.

Abdomen, Acute↗
PubMed1988

Anterior lesser curve seromyotomy and posterior truncal vagotomy for chronic duodenal ulcer: the results at five years.

In one surgical unit, 241 patients have undergone anterior gastric seromyotomy and posterior truncal vagotomy for chronic duodenal ulcer. The postoperative mortality rate was 0.4 per cent. Four patients (1.6 per cent) required a drainage procedure for gastric stasis. The first 66 patients (Group A) were followed prospectively and 58 were available for assessment at 5 years. Eight patients (14 per cent) had developed a recurrent ulcer. In seven of these patients this responded to conservative treatment with H2 receptor antagonists. One patient has required Polya partial gastrectomy for recurrent ulceration. At 5 years 47 patients (81 per cent) were placed in the Visick I or II categories. In the next 175 patients (Group B), the ulcer recurrence rate was 3 per cent, suggesting a learning curve in mastering the procedure. We conclude that the immediate and 5-year results of the first 66 patients are at least comparable with those of highly selective vagotomy. Anterior gastric seromyotomy with posterior truncal vagotomy is an easy and rapid procedure and may be more widely applicable than highly selective vagotomy.

Adult↗
PubMed1987

In the BJS now.

Explore the source record for details and available documents.

General Surgery↗
PubMed1986

Audit of surgical audit.

A clinical audit, run by surgeons with modest clerical assistance, has been incorporated into the routine clinical practice of all hospitals in a large health authority. Data on operations and deaths are integrated into routine clinical recording, and feedback is by annual report containing statistical analyses and critical commentaries and by discussions with colleagues. The results of the first five years show statistically significant falls in the number of reoperations for intra-abdominal complications, retained gallstones, arterial grafts, and amputations and in operative mortality following surgery for benign biliary and pancreatic disease, resection of large bowel for benign disease, operations on aortic aneurysms, and arterial grafts except for aneurysms. Although the audit was designed originally for monitoring and improving quality of care, other uses include monitoring of increasing specialisation and changes in clinical practice, planning surgical services and postgraduate training, and showing the effects of changes in the availability of resources.

Clinical Competence↗
PubMed1985

Mortality and morbidity after anterior lesser curve seromyotomy with posterior truncal vagotomy for duodenal ulcer.

A survey has been performed of the mortality and morbidity of anterior lesser curve seromyotomy with posterior truncal vagotomy in the elective treatment of chronic duodenal ulcer. There was one death in a series of 605 patients due to a myocardial infarction, an operative mortality of 0.16 per cent. There was no case of ischaemic necrosis of the lesser curvature or fundus of the stomach. Eleven patients had symptoms of delayed gastric emptying (1.7 per cent) and seven of these underwent a drainage procedure (1.3 per cent). Postoperative dumping did not occur, significant diarrhoea was present in two patients (0.33 per cent). This operation is relatively simple, quick and extremely safe to perform. It is suggested that the more widespread use of this type of elective surgery for duodenal ulcer might reduce the mortality from the condition.

Chronic Disease↗
PubMed1982

Anterior lesser curve seromyotomy and posterior truncal vagotomy in the treatment of chronic duodenal ulcer.

The value of anterior lesser curve seromyotomy with posterior truncal vagotomy as a simple and safe method of denervating the parietal cell mass without the need for a drainage procedure was assessed in 143 patients with chronic duodenal ulcer at two different centres. There were no early complications directly attributable to the gastric surgery and the operation took less time than truncal vagotomy and pyloroplasty. Postoperative diarrhoea and dumping were not significant difficulties. Basal acid output was reduced by 84.4% and an early positive insulin response within the first three months occurred in 8.75% of patients tested. Satisfactory Visick grades (I and II) were recorded in 93.8% of patients during the early postoperative period.

Adolescent↗