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Biomedical subjects

A A Hendricks

Publications and source records attributed to A A Hendricks.

9 recordsLinked to original sources
PubMed1982

Cutaneous immunoglobulin deposition in primary biliary cirrhosis.

We studied the skin of six patients with primary biliary cirrhosis (PBC) to determine if there is cutaneous deposition of complement and immunoglobulins in PBC. We also investigated serum samples from these patients for the presence of circulating antibodies against nuclear and cytoplasmic antigens. Three of five patients demonstrated immunoglobulins (IgM or IgG) or complement (C3) deposition at the dermoepidermal junction (DEJ) in clinically normal, light-protected skin. Two of six patients had 2- to 5-mm papular-pustular skin lesions as a manifestation of PBC. Serological studies in these patients disclosed low antinuclear antibody titers in three patients and anti-single-stranded DNA antibody titers in the two patients with skin lesions. These histological, immunofluorescent, and serological findings offer further evidence of the occurrence of circulating immune complexes in at least some patients with PBC.

Adult↗
PubMed1981

Erythema annulare centrifugum associated with ascariasis.

Erythema annulare centrifugum (EAC) is a figurate erythema that has been associated with man diverse entities. A case of EAC was related to infestation by the nematode, Ascaris lumbricoides. A careful examination of the patient did not define an immunologic basis for EAC. Results of lymphocyte stimulation tests of the patient showed an immune response to A lumbricoides extracts but not to A suum extracts. This finding is of practical importance, since most laboratoires use A suum extracts in routine skin and serologic tests for human ascariasis.

Anthelmintics↗
PubMed1980

Primary cutaneous aspergillosis.

A 6-year-old boy with acute monocytic leukemia and therapy-induced leukopenia developed multiple necrotizing skin lesions where an intravenous administration unit had been secured to his arm and hand. Biopsy and cultures demonstrated Aspergillus flavus as the etiologic agent without evidence of systemic dissemination. Resolution of the infection occurred following systemic amphotericin B therapy and a granulocyte transfusion.

Amphotericin B↗
PubMed1980

Yellow lunulae with fluorescence after tetracycline therapy.

Yellow lunulae with yellow fluorescence under Wood's lamp examination developed in a patient treated with a high-dose tetracycline hydrochloride regimen for cystic acne after one month of therapy. The clinical findings in other causes of yellow nail pigmentation are reviewed. The Wood's lamp examination is useful in distinguishing tetracycline-induced yellow nails from other causes of yellow nail pigmentation and may be helpful in determining patient compliance with tetracycline hydrochloride regimens of 1 g or more daily.

Acne Vulgaris↗
PubMed1979

Contact dermatitis due to nitroglycerin ointment.

Topical nitroglycerin ointment is among the most effective long-acting vasodilators currently available. We report two cases of contact dermatitis in which patch testing showed allergy to nitroglycerin-containing compounds. The severity of this dermatitis necessitated the discontinuation of topical nitroglycerin therapy in both patients. A potent corticosteroid cream applied once to previous nitroglycerin application sites prevented or minimized this dermatitis and enabled continuation of topical nitroglycerin therapy. Contact dermatitis due to topical nitroglycerin preparations may be more common than is presently realized.

Aged↗