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Biomedical subjects

A A Kassem

Publications and source records attributed to A A Kassem.

5 recordsLinked to original sources
PubMed1979

Antimicrobial activity of chloramphenicol in solid dispersion systems.

The effect of solid dispersion techniques on the antimicrobial activity of chloramphenicol has been studied and it was proven that the antimicrobial activity of chloramphenicol is not affected when the drug is present as a coprecipitate with carbowaxes (4.000, 6.000, 12.000), and PVP 11.000 and 40.000) also in fusion systems with these polymers. In contrast, the antimicrobial activity of the drug is enhanced when it is present in the from of a solid dispersion system.

Chloramphenicol↗
PubMed1979

Availability of norethisterone acetate from combined oral contraceptive tablets.

The availability of norethisterone acetate in HCl (0.1 mol/l) from combined oral contraceptive tablets in the presence of certain proprietary preparations and adsorbent drugs which are used as antacids, intestinal adsorbents and for peptic ulcer was investigated. The percent dissolution of the hormone in the presence of these drugs was greatly reduced depending mainly on the nature of the adsorbent drugs.

Adult↗
PubMed1979

Effect of certain additives on the dissolution rate of chloramphenicol.

A study was conducted on the effect of certain additives on the dissolution rate of chloramphenicol. The effect of adsorbents, natural and synthetic surface active agents, diluents and lubricants was studied. Many of these additives increased the dissolution rate of chloramphenicol from capsules.

Alcohols↗
PubMed1977

Effect of vehicles on the spermicidal potency of certain drugs.

Different spermicidal drugs were formulated into ointments, creams, pastes and jellies and tested for their spermicidal potency on human sperms adopting a modified in vitro technique. Of the formulae tested, those incorporated in Carbopol 934 of polyethylene glycol base exhibited the most prevailing spermicidal activity.

Female↗