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Biomedical subjects

A A Mikheev

Publications and source records attributed to A A Mikheev.

35 records · Page 2Linked to original sources
PubMed1990

[Use of autologous pericardium in plastic surgery of the right coronary artery in patients with ischemic heart disease].

The paper describes the procedure developed by the authors for surgical myocardial revascularization in patients with coronary heart disease (CHD) via direct reconstruction of the ostium and all the segments of the right coronary artery by performing direct endarterectomy and subsequent plasty with free autopericardial flaps. The findings indicate that this surgical method is beneficial for CHD patients. In some cases, it may be the method of choice in the surgical treatment of CHD patients.

Adult↗
PubMed1990

[Aortocoronary bypass in progressive stenocardia].

The authors evaluate the efficacy of aortocoronary shunting in the treatment of 10 patients with progressive angina pectoris (unstable stenocardia) in follow-up periods of up to 12 months after the operation. In none of the patients did angina pectoris or myocardial infarction develop in the indicated postoperative periods.

Adult↗
PubMed1990

[Aortocoronary shunting in patients with newly developed stenocardia].

Aorto-coronary bypass were performed in 10 patients aged from 34 to 55 years 7 to 30 days after the occurrence of angina pectoris for the first time. Coronarography demonstrated stenosis (of more than 75%) of the coronary arteries in all patients. Angina pectoris disappeared and did not recur in postoperative periods of up to 12 months in all cases. Shuntography was carried out 6 weeks after the operation in one patient: the shunt was potent.

Adult↗
PubMed1989

[Formation of pseudoaneurysms at the site of prosthetic surgery of the aorta using a synthetic prosthesis in coarctation].

Two patients who underwent 28 and 20 years ago operation for correction of coarctation of the aorta and its restoration by synthetic dacron prostheses were examined. They had characteristic complaints. Examination by functional and invasive methods revealed changes in the synthetic prostheses which caused the characteristic complaints and elements of the disease. The findings of autopsy were studied in a case of sudden death 25 years after repair of the aorta by a dacron prosthesis in coarctation. Morphological examination revealed essential changes in the synthetic dacron prosthesis which led to complications in the late postoperative period.

Adult↗
PubMed1989

[Aortocoronary shunting in the early period after myocardial infarction].

Fourteen patients aged 34-54 years underwent aortocoronary bypass surgery for early postinfarction angina within 30 days following myocardial infarction. In periods up to 1.5 years after surgery, angina pectoris was not detected in the patients; cases of recurrent myocardial infarction were not registered.

Adult↗
PubMed1984

[Immunochemical study of the degradation of circulating glycoproteins and the neurospecific membrane glycoprotein D2 by cathepsin D of the human brain].

Cathepsin D was isolated from human brain. A consecutive use of affinity chromatography on hemoglobin-sepharose 4B and column chromatography on hydroxylapatite resulted in a homogeneous enzyme (as was demonstrated by SDS polyacrylamide gel electrophoresis) with a molecular weight of about 48,000, 2800-fold purification and 3.4% yield. Incubation of serum proteins in the presence of purified cathepsin D resulted in a gradual decrease of immunoreactive forms of albumin, orosomucoid, transferrin, and other alpha 1, alpha 2 and beta-globulins. The degradation was revealed by crossed immunoelectrophoresis. Crossed affinity immunoelectrophoresis in the presence of ConA showed specific degradation of serum glycoproteins. Rocket immunoelectrophoresis with monospecific antisera raised against human adult brain glycoprotein D2 revealed a rapid and linear degradation of detergent-solubilized and partially purified human membrane glycoprotein D2 by purified cathepsin D. Incubation of glycoprotein D2 in the presence of cathepsin D (30 min, 37 degrees C) resulted in degradation of 95% of specific protein. An exposure of human brain membrane fragments to cathepsin D resulted in linear degradation of membrane-bound glycoprotein followed by an appearance of a soluble immunoreactive form of protein D2.

Blood Proteins↗
PubMedDate not supplied

[Correlation between the precision of analogue-to-digital converter and discretion frequency at the P wave base of the electrocardiogram signal].

Described is the interplay between the quantifications of the ECG signal by time, on the one hand, and by amplitude, on the other hand, at the P wave base. Ratios are suggested that can be used to choose a precision of the analogue-to-digital converter for preset values of P-wave parameters ensuring the detection of the P wave with an error not exceeding one time-quantification pitch.

Electrocardiography↗
PubMedDate not supplied

[Sutures and anastomoses of the aorta and large arteries].

The problems of air-tightness of vascular sutures are discussed. The authors suggested and used in the clinic successfully a double-row buried suture of the anterior wall of the aorta, pulmonary trunk, and femoral artery under conditions of using heparin. The incision for forming the proximal anastomosis in correction of coarctation of the aorta is discussed. A circular suture applied to the aorta and pulmonary trunk with a single thread was developed in experiments and performed in the clinic.

Anastomosis, Surgical↗