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Biomedical subjects

A A Moiseev

Publications and source records attributed to A A Moiseev.

16 recordsLinked to original sources
PubMed1990

[An assessment of the contribution of internal irradiation to the early manifestations of acute radiation sickness in the victims of the accident at the Chernobyl Atomic Electric Power Station].

Materials of the investigation of victims of the accident at the Chernobyl Nuclear Power Plant were used for the estimation of a contribution of exposure with incorporated radionuclides to a course of acute radiation syndrome thyroid and pulmonary lesions. Attention was granted to patients who died as a result of accidental exposure. Dose values of thyroid, pulmonary and total body exposure were given. The severity of the affection of the bronchopulmonary and hypophysial-thyroid systems was assessed. The results of cytogenetic investigations to estimate absorbed doses were represented for some persons. Internal exposure was shown to make a considerable effect on the development of acute radiation syndrome in two persons only, internal whole-body exposure doses being compatible with a total exposure dose.

Accidents↗
PubMed1989

[The diagnosis, clinical picture and treatment of acute radiation sickness in the victims of the Chernobyl Atomic Electric Power Station. II. Non-bone marrow syndromes of radiation lesions and their treatment].

Out of 115 victims to the breakdown, 56 persons had radiation burns, 17 the intestinal syndrome, 80 the oropharyngeal syndrome, and 7 interstitial radiation pneumonitis. In the lethal outcome, of crucial importance were radiation burns (over 40% of the body surface) (19 persons) and radiation pneumonitis (7 persons). The grave intestinal and oropharyngeal syndromes were accompanied by other fatal manifestations of radiation injuries. Hemoperfusion, plasmapheresis, continuous heparinization and administration of freshly frozen plasma did not bring about any improvement. The local use of different remedies under aseptic conditions was the leading method of the treatment of radiation burns in the acute period. Parenteral feeding turned out to produce a beneficial effect in the treatment of the intestinal and oropharyngeal syndromes.

Accidents↗
PubMed1989

[Diagnosis, clinical picture and therapy of acute radiation disease in victims of the accident at the Chernobyl nuclear power station. I. Conditions of irradiation, dose levels, bone marrow syndrome and its therapy].

A follow-up of 115 patients with acute radiation disease resulting from external gamma-beta-radiation confirmed a high value of the previously proposed principles of predicting a degree of severity on the basis of the clinical manifestations of a primary reaction of disease and some syndromes using methods of hematological and cytogenetic analysis. Early isolation of patients with ARD of II-IV degree, selective intestinal decontamination, administration of antibiotics of a broad spectrum of action, antimycotic and antiviral drugs, and gamma-globulin can practically eliminate the risk of development of fatal infectious complications in medullary and transient types of radiation disease. The efficient use of thrombomass transfusion completely prevents development of the thrombocytopenic hemorrhagic syndrome. Experience in bone marrow transplantation requires a review of therapeutic indications.

Accidents↗
PubMed1987

[Calibration of spectrometers for measuring irradiation of humans from incorporated potassium-40].

Combined calibration of 3 spectrometers of human radiations of various design and control measurement of potassium in one and the same group of persons were performed. Causes of divergence were analysed and readings of instruments within +/- 5% were summarized. The importance of selection of a calibration phantom which was radiometrically adequate to the human body and a necessity of establishing correlations between phantom parameters and anthropometric data on man were shown.

Calibration↗
PubMed1984

[Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension].

In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively. These differences depended on the expression of the basic (alkaline) characteristics of the anions of the administered solutions of potassium and sodium and the osmolarity of the administered amount of liquid. Pronounced ion exchange reactions were observed during the administration of KHCO3 solution only, the multiplicity factor of the excretion of sodium and chlorine ions with urine significantly exceeding that of diuresis. During the administration of KCl solutions in the isotonic NaCl solution and 5% glucose, the excretion of sodium and chlorine ions changed strictly in accordance with the changes of diuresis. Similar changes were noted in the administration of the solutions of sodium hydrocarbonate and sodium chloride.

Bicarbonates↗