PubMed Health⌕ Search

Biomedical subjects

A A Morgan

Publications and source records attributed to A A Morgan.

14 recordsLinked to original sources
PubMed1999

The cosmetic outcome in early breast cancer treated with breast conservation.

AIMS: To measure the cosmetic outcome of breast-conserving surgery and identify the factors which influence cosmesis. METHODS: A total of 254 patients with primary breast cancer treated by wide local excision, with or without radiotherapy, were subjectively assessed for cosmesis by a six-member panel using photographic evaluation and objectively by an independent observer using specific measurement. RESULTS: Good to excellent cosmetic results were achieved in 184 (72%) patients on panel subjective assessment and 201 (79%) patients on objective assessment. Good correlation (P<0.001) and agreement were found between the panel's subjective photographic assessment and the objective assessment. The main factors found to affect cosmesis negatively were: medially located tumours; weight of specimen; re-excision procedures; radiotherapy; small breasts and longer scars. CONCLUSION: These cosmetic results, combined with a low local recurrence rate following wide local excision, validate the operative method used.

Adult↗
PubMed1982

Apnoea following suxamethonium: the genetic study of four generations of a family.

Nineteen subjects were investigated as a result of apnoea following the administration of suxamethonium occurring in one member of the family. Examination of the blood for cholinesterase activity, dibucaine number, and fluoride number was carried out and the appropriate genotype determined. The significance of the genetic variation of plasma cholinesterase in relation to suxamethonium apnoea is discussed. Five subject had the genotype Eu1Eu1, seven were of genotype Eu1E1a, three were Eu1Es1, and four Ea1Es1. Nine members of the family were considered to be at risk for the administration of suxamethonium. The appropriate action to safeguard other members of the family following a case of apnoea is outlined. By routine preoperative blood examination, 92 of 100 cases of suxamethonium apnoea resulting from a genetic abnormality of plasma cholinesterase can be anticipated.

Adult↗
PubMed1982

Recurrent gastrointestinal hemorrhage: an unusual cause.

A young man presented with gastrointestinal bleeding which necessitated a partial gastrectomy. No lesion was discovered in the stomach or duodenum. Subsequently episodes of hemorrhage recurred. Barium studies and blood investigations failed to reveal the cause. The observation of skin lesions on the neck led to the diagnosis of pseudoxanthoma elasticum. The importance is stressed of examining the skin in any case of alimentary bleeding of obscure origin.

Adult↗
PubMed1980

Left vocal cord paralysis and dysphagia in mitral valve disease.

Two cases of severe mitral stenosis with both hoarseness, caused by left vocal cord palsy, and dysphagia are described. This combination in the same patient has not, to our knowledge, been previously described. Previous studies have firmly established that vocal cord paralysis in mitral stenosis is a result of compression of the left recurrent laryngeal nerve as it passes around the aortic arch. It is suggested that dysphagia may also develop as a result of neurological damage, in this case to autonomic nerve plexuses supplying the oesophagus, leading to abnormal peristalsis and enabling external compression by a tense left atrium sufficient to cause symptoms

Adult↗