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Biomedical subjects

A A Musa

Publications and source records attributed to A A Musa.

27 records · Page 2Linked to original sources

Mathematical modeling of fetal organ growth using the Rossavik growth model: IV. Lung.

Growth of the fetal lung has been monitored by left lung area (LLA), right lung area (RLA), and total lung area (TLA) from 14 to 41 weeks menstrual age in 116 normal Japanese fetuses. Growth of the fetal heart and chest has also been monitored by heart area (HA) and chest area (CA), respectively. Growth curves for these parameters have been determined by using a Rossavik growth model [p = c(t)k+s(t)]. R2 values of 95.3%, 90.3%, 89.0%, 88.7%, and 92.1% were obtained for CA, HA, LLA, RLA, and TLA, respectively. Variability analysis indicated a progressive increase in variability with fetal age for these five parameters. Variability data were used with the growth curve models to determine standard curves for these parameters. These standard curves provide a superior means for evaluating the normal fetal lung growth in the fetus and for identifying pulmonary hypoplasia in utero.

Female↗

Serum CA-125 and 17 beta-estradiol in patients with external endometriosis on danazol.

Serum concentration of CA-125 and 17 beta-estradiol (E2) were measured by radioimmunoassay in 40 patients with stage III or IV endometriosis to evaluate their usefulness in assessing the outcome of disease. Patients were categorized into good responders and poor responders depending on the result of the second-look laparoscopy 8 weeks after danazol therapy. CA-125 decreased significantly in all subjects after initiation of treatment. However, after 12 weeks of treatment a significant increase (p less than 0.05) in serum CA-125 was noted in the poor-response subjects as compared to the good-response subjects. In addition, 8 weeks after treatment CA-125 levels in the poor-response group were significantly higher (p less than 0.001) than in the good-response group. On the other hand, in the good-response group, E2 levels decreased for 8 weeks during danazol therapy to return to almost basal levels after 12 weeks, while in the poor-response group E2 levels did not change as compared to pretreatment levels. We conclude that the determination of CA-125 and E2 may be helpful in assessing the response of patients with advanced endometriosis on danazol treatment.

Antigens, Tumor-Associated, Carbohydrate↗

Methods of assessing spinal radiographs in scoliosis are functions of its geometry.

The most important feature of scoliosis is the lateral curvature of the spine. It can be treated either conservatively or by surgery; however, treatment choice depends mainly on curve progression which is determined by frequent curve assessment. This is a review of methods of curve measurement and proof of the relationship between them.

Disease Progression↗

Mature sacrococcygeal teratoma: a case report and literature review.

BACKGROUND: Sacrococcygeal teratomas are derived from embryonic germ cell layers. They present mostly in infancy and are extremely rare in adults; with an associated risk of malignancy. Modern imaging technique may be helpful to delineate the extent of the mass but surgical excision is generally indicated at the time of detection. PATIENTS AND METHODS: A case report is presented with a review of literature utilising MEDLINE, Microsoft Net and Yahoo search engines. RESULTS: A three day old female baby presented with a mature sacrococcygeal teratoma containing well-developed limb buds. She had surgical excision and primary repair with good results. A two-year follow up utilising serial serum alpha-fetoprotein assay and CT Scan revealed no evidence of tumour recurrence. CONCLUSION: Sacrococcygeal teratoma is a rare tumour that may be benign or malignant. Complete excision is the primary therapy and is adequate if the tumour is benign. Chemotherapy and radiotherapy are however indicated in malignant cases and in recurrence after previous excision.

Biopsy↗

A preliminary report of fine-needle aspiration biopsy in superficially accessible lesions in children.

BACKGROUND: Fine-Needle Aspiration Biopsy (FNAB) is a diagnostic technique which has achieved widespread use and acceptance. Its clinical use has continued to widen with the availability of more sophisticated methods of imaging. Its minimal invasiveness, cheap cost and easy application make it a technique of choice in investigating swellings even in children. AIMS AND OBJECTIVES: To investigate the reliability, safety and diagnostic value of FNAB in superficial masses including lymph nodes in children. PATIENTS AND METHODS: Superficial masses and lymph nodes of twenty consecutive children aged 2-13years were subjected to FNAB. Open biopsies were also performed on them to validate the FNAB. All specimens were subjected to examination by a cytopathologist and a histopathologist. RESULTS: Nine of the patients (45 %) had malignant diseases (lymphoma and osteosarcoma); seven had tuberculous lymphadenopathy while four had reactive lymphadenitis. Open biopsies corroborated these findings. There were no false-negative or false-positive cytology results from aspirates. There were no complications related to the procedures. CONCLUSION: Fine-needle aspiration biopsy is a reliable, safe, less invasive and relatively cheaper alternative method of establishing a pathologic diagnosis, compared to open biopsy, in children.

Adolescent↗

A portable Bohler-Braun splint.

Bohler-Braun is used in the conservative management of fractures of the lower limb. The splint is cumbersome making it difficult to work with in situation where compactness of the splint is required. This work is a modification of the splint into a portable version.

Equipment Design↗

Indigenous hospital technology in Nigeria: problems and recommendations.

In Nigeria, after gaining independence there arose a national desire for industrialization in order to reduce the high cost of sustaining national development. This desire has its accompanying problems which are examined with reference to indigenous hospital technology. Solutions to these problems are also suggested.

Biomedical Technology↗

How to adapt an ordinary drilling machine for orthopaedic surgery.

An orthopaedic drilling machine has number of revolutions per minute (r/min) < or = 750. This low r/min. accounts for low friction and less tissue damage during bone drilling. This is an advantage over the ordinary drilling machine whose r/min. > 2800. A method of converting it into an orthopaedic drilling machine is described here.

Bone and Bones↗