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Biomedical subjects

A A Panov

Publications and source records attributed to A A Panov.

At least 19 recordsLinked to original sources

Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells.

Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca(2+) membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.

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[The effect of sodium nitroprusside on the membrane potential and mechanical tension of the smooth-muscle cells in the rat aorta].

The rat aorta smooth muscles were contracted and depolarised with high potassium or phenylephrin solution which was followed by a relaxation and repolarisation after sodium nitroprusside administration. The latter effect was decreased az a combined action of phenylephrin and high potassium solution. Nitroprusside seems to act through a cGMP-dependent potassium transient activation of the smooth muscle cell membrane.

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[The age-related characteristics of changes in osmotic and ionic homeostasis in spontaneously hypertensive rats].

The 3-month old SHR differ from the WKY rats in that the former have an increased osmolality, concentration of albumins, activity (but not the concentration) of sodium and a reduced activity of potassium. The shifts in the albumins concentration occur, mainly, on account of the amino acid phenylalanine. The gradient increase of the sodium and potassium concentration between the plasma and muscular tissue in followed by a slight hyperpolarisation of the muscle fibers, a drop in the lability and a increase in pO2. The above shifts of homeostatic parameters were not revealed in the SHR and WKY rats of 1.5 and 6.0 months of age.

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The histology of the cerebral neurosecretory system in several representatives of Cleroidea (Coleoptera, Insecta).

In Thymalus sp. (Peltidae), Melambia tekkensi (Trogositidae), Trichodes apiarius and Thanasimus formicarius (Cleridae), the composition of cerebral neurosecretory cells (NSC) is similar to that found earlier in Meloidae (Panov 1985a) and Tenebrionidae (Melnikova and Panov 1981; Melnikova 1983). 20 type I NSCs, 16 type II NSCs, 4 type III NSCs, several type IV NSCs and 4 type V NSCs are characteristic of their pars intercerebralis. On the other hand, a reduction of type I and II NSC number to 10 and 12 cells, respectively, was revealed in Malachius affinis, Malachius viridis and Malachius bipustulatus (Melyridae). There are 6 large dorsolateral NSCs and 2 lateral ones in each brain hemisphere of most Cleroidea studied. Their retrocerebral endocrine complex is similar to that of most polyphagous coleopterans: a single nervus corporis cardiaci leaves each brain side, the corpora cardiaca are fused with lateral aorta walls and corresponding corpora allata.

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The cerebral neurosecretory cells and retrocerebral endocrine complex in several representatives of staphyliniformic beetles (Coleoptera, Staphyliniformia).

The cerebral neurosecretory cells and retrocerebral endocrine complex were histologically studied in 20 species representing 4 families of the series Staphyliniformia (Coleoptera, Polyphaga). In their brains, the neurosecretory cells are clustered in one usually unpaired median group of the pars intercerebralis and in paired dorso-lateral and lateral groups. Up to 5 distinct neurosecretory cell types were found in the pars intercerebralis. In Hydrophilidae, Staphylinidae and in Nicrophorus species (Silphidae), the median group includes generally 20 type I neurosecretory cells and 16 type II neurosecretory cells. In Histeridae and Silphini species, the number of type I and II neurosecretory cells reaches 60-90 each. In staphyliniformic beetles, as in other Coleoptera, the number of type III and V neurosecretory cells is equal to 4. The corpora cardiaca are paired and fused with lateral aorta walls. In Hydrophilidae, Staphylinidae and Silphini, two pairs of the nervi corporis cardiaci innervate the corpora cardiaca. There is only one pair of the nervi corporis cardiaci in Histeridae and Nicrophorus species. The corpora allata join directly the corresponding corpora cardiaca. They contain frequently the neurosecretory products of cerebral neurosecretory cells.

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The cerebral neurosecretory cells of cicadas (Homoptera: Cicadidae).

The cerebral neurosecretory cells (NSCs) of three cicadid species (Tibicen plebeja Scop., Cicada orni L. and Melampsalta musiva (Germ.) were studied in sections stained with PTh-PF, AB-PF and PThPh. There were revealed numerous scattered NSCs of the cellular cortex, three paired groups (M 1, M 2, M 3) of the median NSCs homologous to the corresponding NSC groups of Holometabola, and lateral NSCs not forming a single compact group. The group MI located in the pars intercerebralis was found to consist at least of four NSC types in Tibicen plebeja and in Cicada orni and of six NSC types in Melampsalta musiva. Four cells of two groups M 2 were observed at the basis of MI-group, and four NSCs of two M 3-groups - in the anterior cellular cortex of the protocerebrum. The nerve fibers of M 1-group NSCs send out side branches lateralwards into the dorsal protocerebral neuropile, then they cross with their contralateral counterparts and leave the brain within the nervus corporis cardiaci I. The M 2- and M 3-cell fibers do not join those of MI-group NSCs. The M 2-cell fibers could not be traced for a long distance, whereas M3-cell fibers were observed to pass apparently into the circumoesophageal connectives. The cerebral neurosecretory system of Cicadidae seems to be similar in its organization level to that of Neuroptera and is considered as less advanced that that of Geocorisae (Heteroptera).

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