Biomedical subjects
Publications and source records attributed to A A Platonova.
2500 records of cardiointervalograms and 24-h ECG monitoring for 1530 arrhythmic patients have been analysed. This complex approach to analysis of cardiac arrhythmia allowed a more accurate differential diagnosis, more detailed visualization of rhythmic abnormalities, more advanced analysis of neurovegetative background of developing rhythmic shifts.
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Heart rhythm was studied by computer in 67 patients with atrial flutter of different etiology. It was discovered that respiratory activity has an influence on the conduction of atrial flutter waves to the ventricles. In the majority of cases, the conduction of atrial waves to the ventricles is multiple with a constant conduction ratio. However, in some cases the conduction of atrial flutter waves via the atrioventricular system occurs according to the Samoilov-Wenckebach periodicals. In the latter case and in atrial flutter with a conduction ratio of 4:1, one-third of patients manifest, after the recovery of the sinus rhythm, atrioventricular blockade, grade 1.
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Computer served to study by automatic analysis the structure of the cardiac rhythm in 190 patients: 123 patients after removal of the persistent form of atrial fibrillation, 24 with neuro-circulatory dystonia and 43 healthy individuals. Sino-atrial block with Samoilov-Wenkebach periods was recorded in 26 individuals. The characteristic changes of the cardiointervalogram in the given disorder of intracardiac conduction are described, which facilitates diagnosis considerably. The sino-atrial block with Samoilov-Wenkebach periods in the observed was not accompanied by clinical symptoms and exerted no untoward effects on the distant results of electro-impulse therapy in patients with persistent forms of atrial fibrillation.
The results of studying the electrical activity of the atria in 53 patients with cardiac fibrillation by means of a special digital computer system are discussed. On the strength of the aggregate of amplitude, rate, and morphological characteristics, three varieties of fibrillation waves are distinguished. It is shown that in the absence of cardiotropic therapy, the principal regular features in the distribution of the ff waves according to the frequency ranges are preserved in one and the same patients for a long period of time. A characteristic dynamics of changes in atrial activity during treatment with preparations of digitalis was disclosed, which may be an additional criterion of digitalization. A connection was revealed between the changes in atrial activity during treatment with digitalis preparations and the characteristic dynamics of the ventricular rhythm structure. The absence of such correlative connection may be evidence of the possible occurrence of atrioventricular block after restoration of the sinus rhythm.
The structure of cardiac rhythm was studied with the help of specialized computers during digitalization in 60 patients with atrial fibrillation of different etiology. The reduction of the heart contractions rate under digitalization is accompanied by certain changes in the structure of cardiac rhythm: the arrhythmic pattern of the ventricular contractions increases with a predominant growth of the number of long R--R intervals, the transitions from short intervals to longer ones become sharper, and portions of a relatively stable ventricular rhythm appear. Three main types of dynamics of the rhythm structure were distinguished on the basis of the changes in the interval R--R histogram. The described changes in the structure of cardiac rhythm are not specific, but when Digitalis drugs are used alone they can be used as additional criteria for digitalization.
The autocorrelation funtion of the electrocardiographic signal in the V1 lead is approximated by the formula of an attenuated consinusoid. Parameters are singled out (median period, attenuation factor) to characterize the atrial activity. A procedure for recording the auto correlation function is described and optimal conditions of its registration are studied. First results following clinical application of the method are reported.
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