Biomedical subjects
Publications and source records attributed to A A Podkolzin.
Electrochemically activated systems normalized activity of antioxidant enzymes catalase, peroxidase, and superoxide dismutase. The baseline activity of antioxidant enzymes considerably varies in humans and animals. This effect of electrochemically activated systems having negative oxidation-reduction potential was probably related to a training effect of excess electrons.
The function of the blood-salivary barrier at different stages of orthodontic treatment of secondary partial adentia depends on the psychoemotional status of a patient. Such a conclusion was made after investigation of mixed human salivary pools. Total sialometry was carried out for objective evaluation of the level of salivary secretion. Salivary secretion was measured and the psychoemotional status of a patient was assessed using M. Luscher's 8-color test. During dental preparation the psychological status was assessed as 21.2 +/- 1.7 scores, versus normal 11.3 +/- 0.03 score. Salivation rate during dental preparation was 1.41 +/- 0.02 ml/min versus normal rate of 0.527 +/- 0.03 ml/min. The results indicate a relationship between psychological reactions of a patient and the manipulations in the oral cavity. These data may be used for assessing the status of a patient in general and, specifically, the stress index.
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The special feature of weak-pulse current effects on immune rosette formation has been investigated in mice. Stimulation of PFC generation could be made in the murine spleen 4 days after immunisation on 5-10-minute weak-pulse current exposure during 1 hour after immunisation. The parameters of signal was: 543 kHz frequency and triangular or quadratic signal form, that is typical for resonance mechanism of different stimuli. The resonance mechanism may be the basis for the influence of low-intensity factors on the body, which allows the low-intensity physical and other exposures to be used in clinical practice.
In two series of experiments on 61 dogs it was found that from all the nerves approaching the heart, the largest are on the ascending aorta, pulmonary trunk and pericardium transilicual tuck along which they cross the left pulmonary artery on the way to the dorsal surface of this organ. These nerves are able to provide the adequate heart activity under cardiovascular system loading. It is they that should be primarily used for transplanted heart reinnervation.
It has been established in 23 experiments on dogs that during asphyxia the reactions of denervated heart which were directed toward compensation of hypoxia in the whole organism and towards preservation of myocardium from hypoxia damages were slower than that in the norm. All these processes led to the overloading of myocardium.
It has been executed 26 experiments on dogs in order to investigate the changes of haemodynamics during narrowing of ascending aorta and brain ischaemia. It has been setted during investigation, that cardiovascular system possesses high compensatory abilities. This system fully restored the disorders in blood circulation during 3 minutes of occlusion of brachiocephalic trunk or during 5 minutes of narrowing. The restoration of normal blood circulation after 5 minutes leads to normalization of indicators of haemodynamics also in 5 minutes and does not lead to decompensation of cardiac function. The heart decreases the rate of contractions in order to support the high level of its force in such a conditions.
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