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Biomedical subjects

A A Rene

Publications and source records attributed to A A Rene.

6 recordsLinked to original sources
PubMed1995

Mortality preventable by medical intervention: ethnic and regional differences in Texas.

An examination of mortality from 12 causes of death was tabulated for the state of Texas for residents in the Lower Rio Grande Valley; for residents of border counties; for residents of Dallas, Harris, and Tarrant counties, along with residents of east Texas from 1980 to 1989. The ninth revised edition of the International Classification of Diseases was used to categorize causes of mortality. The mortality data were obtained from mortality data tapes obtained from the Texas Department of Health and archived at the University of Texas School of Public Health. From 1980 to 1989, an average of 1543 deaths per year was attributed to these 12 selected causes in Texas. Thirty-two percent of deaths were due to hypertensive heart disease, 30% to pneumonia and bronchitis, 11% to cervical cancer, and 6% to rheumatic fever. Pneumonia and bronchitis were the leading causes of death among those aged 15 to 44 years.

Adolescent↗
PubMed1974

Phase transition of gonococci in mammalian cell cultures.

Neisseria gonorrhoeae was cultivated in mammalian cell cultures in an effort to determine if this environment will elicit a T4 --> T1 transition. Of four avirulent (T4) isolates tested, only one, H4, yielded T1 colonies. This change was consistently obtained in HeLa, WI-38, and MK2 cells, even when the multiplicity of the gonococcal infection was less than 1 per culture. Growth of the gonococci took place primarily on the surface of the cells, as demonstrated by light and electron microscopy, but occasional bacteria were undoubtedly intracellular. T1 colonies were seen at 24 h and were the major population at 48 h. This shift was favored by the presence of viable cells, since smaller yields of T1 were obtained when the cells were irradiated or heat inactivated. It was also favored by low pH, since T1 recovery was reduced when the buffering capacity of the medium was increased. Although the results suggest that T1 gonococci derived from H4 have a selective advantage over T4 in cell cultures, this is not true of all T1 and T4 colony types. F62 T4, which does not undergo a T4 --> T1 shift, propagated as well as T1 in HeLa cell cultures. The change in colony type of strain H4 to T1 was accompanied by formation of pili and by gain in capacity for deoxyribonucleic acid-mediated transformation. It is concluded that gonococci can undergo T4 --> T1 phase transition in mammalian cell cultures, but this property is not retained by all strains.

Animals↗