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Biomedical subjects

A A Salman

Publications and source records attributed to A A Salman.

7 recordsLinked to original sources
PubMed2000

Long-term follow-up of pregnant women after percutaneous mitral valvuloplasty.

The aim of this study was to evaluate long-term clinical follow-up and echocardiographic data on pregnant patients with mitral stenosis who underwent percutaneous mitral valvuloplasty (PMV) in our center and the development of their infants. PMV has proven to be an effective alternative to treat pregnant patients with mitral stenosis. However, long-term outcome of these patients, as well as the potential harmful effects caused by radiation on their infants, still awaits to be determined. From January 1988 to February 1999, 30 pregnant women (mean gestational duration, 24.95 +/- 5.59 weeks) underwent PMV. Twenty-three (77%) were subsequently followed by a medical interview during 5.33 +/- 3.12 years. Clinical variables such as NYHA functional class (FC), the need of a repeat PMV or surgical procedure, the presence of embolic events, and mortality rate were evaluated during follow-up. Mitral valve area, mean transmitral gradient, and the presence of mitral regurgitation were also assessed by Doppler echocardiography. Clinical data on the development of the infants were obtained from the assistant pediatricians. All patients were in NYHA FC III or IV before the procedure. During follow-up, 91% of them were in FC I and II. Two patients (9%) who had remained in FC III underwent a repeat successful PMV; no further surgery was required. There were no embolic events or death related to the procedure. Echocardiography showed an initial increase in mitral valve area from 1.14 +/- 0.22 cm(2) to 2.01 +/- 0.21 cm+/- (P < 0.0001). During long-term follow-up, it decreased to a mean of 1.75 +/- 0.24 cm(2) (P < 0. 0001). Initial transmitral valve gradient decreased from 17.73 +/- 4. 56 mm Hg to 5.91 +/- 1.80 mm Hg (P = 0.0001) and 8.95 +/- 3.58 (P = 0.002) during long-term follow-up. Twenty one children (96%), aged 4. 91 +/- 2.8 years, showed normal growth and development, and no clinical abnormalities were observed. These favorable long-term results suggests PVM to be the procedure of choice to treat pregnant women with mitral stenosis who remain in FC III or IV despite adequate medical therapy. No harmful effects due to the use of radiation were observed in the children.

Adolescent↗
PubMed2000

Adaptive linkage crossover.

Problem-specific knowledge is often implemented in search algorithms using heuristics to determine which search paths are to be explored at any given instant. As in other search methods, utilizing this knowledge will more quickly lead a genetic algorithm (GA) towards better results. In many problems, crucial knowledge is not found in individual components, but in the interrelations between those components. For such problems, we develop an interrelation (linkage) based crossover operator that has the advantage of liberating GAs from the constraints imposed by the fixed representations generally chosen for problems. The strength of linkages between components of a chromosomal structure can be explicitly represented in a linkage matrix and used in the reproduction step to generate new individuals. For some problems, such a linkage matrix is known a priori from the nature of the problem. In other cases, the linkage matrix may be learned by successive minor adaptations during the execution of the evolutionary algorithm. This paper demonstrates the success of such an approach for several problems.

Algorithms↗
PubMed1996

[Use of the Palmaz-Schatz stent in the acute phase of myocardial infarction in a patient with cardiogenic shock].

A 56-year-old female patient underwent myocardial revascularization with three saphenous bypass grafts. One month after surgery she had an acute myocardial infarction with cardiogenic shock and was treated with a Palmaz-Schatz stent implantation in the left main coronary artery (that was occluded) and a PTCA of the graft to the right coronary artery. The in hospital outcome was uneventful and angiographic study after six months showed no restenosis and important improvement in the left ventricular function.

Angioplasty, Balloon, Coronary↗
PubMed1993

[Echocardiographic relation criteria. A new selection method for mitral valvotomy with balloon catheter].

PURPOSE: To find out new subjects that could be useful to select patients between 9 and 12 points, according to Block's Criteria, to mitral balloon valvotomy. METHODS: One hundred and forty patients underwent mitral balloon valvotomy. Among them, 29 (21%) had between 9 and 12 points. These patients were divided into two groups: group A-patients with mitral valve area > or = 1.5cm2, immediately after balloon valvotomy and in the follow-up period; group B-patients with mitral valve area < 1.5cm2 immediately after or during the follow-up period, patients with severe mitral regurgitation after the procedure and patients who died in the follow-up period. All patients were analyzed by echocardiographic relation criteria (ERC): calcification + subvalvar disease/thickness + mobility. Each one was quantified from 1 to 4 points according to the degree of valvular disease. RESULTS: Group A was composed of 17 (51%) and group B 12 (41%) patients. The variables age, sex, previous mitral commissurotomy and atrial fibrillation did not show difference between groups. In group A mitral valve area (cm2) increased from 1.15 +/- 0.25 to 1.97 +/- 0.26 (p < 0.00001) keeping stable during the follow-up period. In group B percutaneous mitral balloon valvotomy resulted in an increase from 1.26 +/- 0.19 to 1.77 +/- 0.16 (p < 0.00001), however, there was an important decrease in the follow-up period to 1.34 +/- 0.15 (p < 0.00001). The ERC showed that all group A patients had a relation < 1. However, in group B, 10 patients (83%), the relation was > or = 1, and in only 2 patients (17%) was < 1 (p < 0.00001). CONCLUSION: The group of patients between 9 and 12 points in the Block's criteria is heterogenic, therefore, each case might be evaluated individually and the echocardiographic relation criteria should be used in order to select these patients to the procedure.

Adult↗
PubMed1989

Malignant fibrous histiocytoma of the anal canal. Report of a case and review of the literature.

Malignant fibrous histiocytoma is a pleomorphic sarcoma that classically arises in the extremities and metastasizes to the lungs and regional lymph nodes. A review of the literature revealed only four previous cases of primary gastrointestinal malignant fibrous histiocytoma, all of which were treated by resection. This report describes a unique case arising in the anal sphincter that was treated by abdominoperineal resection and radiotherapy. The pathology of the condition, including immunocytochemical methods used to identify the tumor and its likely cell of origin, is discussed. The importance of long-term follow-up with repeated chest x-ray and local lymph-node examination is emphasized.

Adult↗
PubMed1989

[Mitral valvuloplasty with balloon catheterization in pregnant patients. Report of 3 cases].

The authors report on three pregnant patients with mitral stenosis with heart failure in functional class IV (NYHA) unresponsive to clinical treatment. They were submitted to mitral valvuloplasty, with significant clinical improvement, and were, hence, asymptomatic. Despite the small number of cases, it may be concluded that the procedure is simple and safe, which can be attested by the successful results.

Adult↗