Biomedical subjects
A A Satir
Publications and source records attributed to A A Satir.
Morphology of the spleen and lymph nodes in fatal visceral leishmaniasis.
Histological appearances of the spleen and lymph nodes were analysed in twenty fatal cases of human visceral leishmaniasis from Sudan. Marked atrophy of the splenic white pulp was associated with necrosis and fibrosis of thymus-dependent area, accumulation of parasite-containing histiocytes and plasma cell hyperplasia. Depletion of small lymphocytes in the paracortical areas of the lymph nodes was accomplained by proliferation of plasma cells and histiocytes in the paracortex. Depletion of small lymphocytes in thymus-dependent regions of lymph nodes and spleen is viewed as arising from immune suppression associated with antigen overloading or other factors, which may impair those aspects of lymphocyte-macrophage cooperation that are presumably necessary to kill the invading parasites.
Salmonellosis complicating schistosomiasis in the Sudan.
Salmonella typhi or Paratyphi A was isolated from the blood in 16 out of 21 Suanese patients who had prolonged fever of one of 10 months' duration and hepatesplenic schistosomiasis. Most patients had severe anaemia. The serum alkaline phosphatase was raised in 16 patients. Bilharzial lesions were demonstrated in the liver biopsies of 10 patients. Three patients had in addition the nephrotic syndrome and moderate proteinuria was present in nine other patients. Changes of proliferative glomerulonephritis were noted in the renal biopsies of two patients with the nephrotic syndrome. Treatment with chloramphenicol cured the salmonella infection in all patients, reversed the raised alkaline phosphatase and the proteinuria, and led to a marked reduction in the size of the hepatosplenomegaly.
The pathology of schistosomiasis in Sudan.
The pathology of schistosomiasis in an autopsy material consisting of medico-legal cases and unclaimed bodies in the Sudan is described. The limitations of this type of study are pointed out. S. mansoni-infection and S. haematobium-infection occurred with a frequency of 14.3 per cent and 4.5 per cent of autopsies respectively. There was a geographical difference in the severity of S. mansoni-infection in two endemic areas in the country; it was particularly severe in patients coming from Bor area in the Southern Sudan. In autopsies with S. mansomi-infection intestinal polyposis and cor pulmonale were rarely encountered. The distribution of eggs in the tissues, using digestion studies, and the relationship of tissue egg load to pathology are reported and discussed.
Burkitt's lymphoma in the Sudan.
During the period 1962-73 twenty-nine cases of Burkitt's lymphoma were seen and examined histologically in Khartoum, Sudan. Burkitt's lymphoma formed 20% of the cases of childhood lymphomas. The average age at presentation was 6.8 years and the male to female ratio was 3.8:1. The clinical features, the anatomical localization and histological appearances were similar to those reported in the literature. The geographical distribution of the tumour showed close correlation to that of holo- or hyperendemic malaria.
Tumor of the mandible caused by Madurella mycetomil.
Explore the source record for details and available documents.
Crohn's disease in three Sudanese patients.
Explore the source record for details and available documents.
Some aspects of the surgical pathology of schistosomiasis in the Sudan.
Explore the source record for details and available documents.
Morphological observations on visceral leishmaniasis in the Sudan.
Explore the source record for details and available documents.
Proceedings: Preliminary report on the pathology of the nephrotic syndrome in Sudanese patients.
Explore the source record for details and available documents.
Proceedings: Some aspects of the surgical pathology of schistosomiasis in the Sudan.
Explore the source record for details and available documents.
Incidence of G-6-PD deficiency and abnormal haemoglobins in the indigenous and immigrant tribes of the Sudan.
Explore the source record for details and available documents.
Highlights on the etiology of keloid.
The keloid phenomenon is old and perplexing. Many hypotheses were advanced to account for keloid growth but none of them provided a satisfactory explanation for the clinical manifestations of the disease. To solve the mystery of keloid detailed clinical studies coupled with laboratory tests were undertaken on keloid and non-keloid individuals; these highlighted the determinants of the disease and paved the way to the formulation of the Sebum Auto-immune Theory. The latter provided valid explanations for the clinical manifestations of the disease and indicated a rationale for new trends of management.