[Immunology problems of peptic ulcer].
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Biomedical subjects
Publications and source records attributed to A A Sheptulin.
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Some subjective and objective symptoms, that are believed to be specific of peptic ulcer, were analyzed in 425 patients with endoscopically confirmed gastric ulcer. It was noted that the pain syndrome may have variants while pain after meals remains a typical sign of gastric ulcer. But asthenic habitus, tendency to sinus bradycardia and arterial hypotension, the absence of a coated tongue, and the tendency to erythrocytosis and decelerated ESR were not typical for the observed patients. The results suggest that some traditional concepts of typical clinical picture of peptic ulcer should be revised.
Patients with association of peptic ulcer and essential hypertension were found to form a heterogeneous group. Examination of this patients' group made it possible to distinguish certain clinical variants of such an association. Patients who first developed essential hypertension and then peptic ulcer were established to have a severe pattern of essential hypertension, unmarked and little symptomatic clinical picture of peptic ulcer, to be characterized by proneness to the complicated disease course. These features together with vascular lesions identified in the gastric submucosal layer, running their course as hypertonic microangiopathies permit attribution of the indicated ulcerations to the group of symptomatic gastroduodenal ulcers. In cases of association of peptic ulcer and essential hypertension, hemiton that suppresses the processes of gastric secretion was found to be the drug of choice.
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