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Biomedical subjects

A A Tarasov

Publications and source records attributed to A A Tarasov.

At least 19 recordsLinked to original sources

[Antibacterial therapy of acute sinusitis in outpatient practice: results of a multicenter trial].

Now there is no generally accepted practice of antibacterial therapy of acute sinusitis in outpatient clinics of Russia. Choice of antibacterial drugs is often made without consideration of the most probable causative agents of the infection. Out-of-date antibiotics used in many cases do not satisfy modern requirements. Clinically essential features of pharmacokinetics are in some cases ignored. Parenteral administration is often unjustified, combined antibiotic treatment is not always validated.

Acute Disease↗

[Prognosis in the outcome of relaparotomy].

The analysis and processing with the use of a special method of 54 direct observations and 342 case records of the patients with early postoperative intraabdominal complications were carried out. A method for syndrome prediction of the outcomes of relaparotomy has been developed. The syndromes of the most significant predictive value have been revealed: those of intoxication, respiratory and hepatorenal failure, impaired hemodynamics and electrolytic metabolism, hemocoagulation. Use in clinical practice of the method mentioned as well as the methods promoting timely detection of the intraabdominal complications permitted to reduce lethality after relaparotomy from 21.4 to 15.3%.

Adolescent↗

[Intra-abdominal hemorrhages in the early postoperative period and their diagnosis].

In the period from 1977 to 1987, after 13,306 operations carried out on the abdominal organs in the clinic, intra-abdominal hemorrhages occurred in 34 (0.25%) patients which had to de managed by emergency relaparotomy. From analysis of case records (28 taken from the archives and 6 of patients who were under observation) of the relationship between the large number (195) of signs represented by a block of clinico-laboratory and radiological data, an integral diagnostic criterion of intra-abdominal hemorrhages was obtained. The diagnostic significance of the criterion was 98.6%. Its practical application comes to recognition of intra-abdominal hemorrhage by identifying the symptoms and syndromes found in the patient with this early postoperative complication with the symptoms and syndromes composing the integral criterion. A revealed integral diagnostic criterion is a concrete indication for undertaking emergency relaparotomy.

Abdomen↗

[Indications for relaparotomy in acute postoperative intestinal obstruction].

For the period of 1977-1987, operations on the abdominal organs were performed in 13,306 patients. Of them, 115 (0.86%) developed 1 to 21 days after the operation acute ileus requiring the performance of emergency relaparotomy. Lethality in this complication was 33.9%. A retrospective analysis of 103 case records and observations on 12 patients who underwent at the early postoperative period emergency laparotomy for acute ileus were performed. The data were entered on a formalized card. The material was processed by means of a computer. The integral criteria for diagnosis of acute postoperative ileus which permitted to predict with an accuracy of 99% the complication serving an indication for relaparotomy were developed.

Abdomen↗

[Incidence of development and the results of treatment of post- operative peritonitis].

In the clinic at the period of from 1977 to 1987 after 13,006 operations on the abdominal organs, 185 patients (1.4%) ranging in age from 16 to 89 years developed peritonitis. The lethality after relaparotomy performed within the first 24 hours of the complication development was 15.9%, later on--73.7%. In spite of the large extent and trauma of radical relaparotomy, the lethality after it was 56%, after palliative one--90%. Timely is the performance of relaparotomy within the first 6 h from the moment of the complication development, in prolongation of the time to 7-12 h, the lethality was 12.5%.

Abdomen, Acute↗

[Primary peritonitis in children].

The results of treatment of 219 children with "primary peritonitis" are analysed. Most patients (73.5%) were under 7 years of age. The simple form of primary peritonitis was encountered in 158 (72.1%) and the toxic form in 61 (27.9%) patients. Significant disorders of humoral (B-system) and cellular (T-system) immunity as well as combined incompetence of the neutrophil intra-leukocytic microbicidal system were revealed. In 72% of girls a relation was detected between the occurrence of primary peritonitis and the condition of maturation of the genitalia. All the children were treated by operation and recovered.

Antibody Formation↗

[Optimization of diagnosis of postoperative peritonitis].

The syndrome approach to diagnosis of the postoperative intraabdominal complications was used. Analysed were 170 case records and 15 observations of the patients with postoperative peritonitis. The data were registered in a specially compiled for every patient formalized card. Materials were computer-processed. The integral criterion for diagnosis of postoperative peritonitis has been obtained.

Humans↗