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Biomedical subjects

A Abdel Fattah

Publications and source records attributed to A Abdel Fattah.

8 recordsLinked to original sources

Transcutaneous electrorectography: human electrorectogram from surface electrodes.

The rectal electric activity or electrorectography was recorded transcutaneously in 24 healthy volunteers (mean age 39.6 years). A silver-silver chloride electrode was applied lateral to each of the two sacroiliac joints, and a third one was placed midway between the left greater trochanter and the ischial tuberosity. The reference electrode was applied to the right lower limb. At least two 20-min recording sessions were performed for each of the 24 subjects. In addition, an intrarectal electrorectographic recording was done in 10 of the 24 subjects using silver-silver chloride electrodes attached to the rectal mucosa by suction. Pacesetter potentials (PPs) were recorded transcutaneously. The wave was triphasic with a small positive, a large negative and another small positive deflection. PPs had a regular rhythm and were reproducible. The mean frequency was 3.1 cycles/min. The transcutaneously recorded PPs could be confirmed by the intrarectal route. Both routes had similar electrorectographic recordings, except for the action potentials (APs) which did not show in the transcutaneous electrorectogram. In conclusion, the study demonstrates that PPs could be recorded transcutaneously. Transcutaneous electrorectography is simple, easy, reproducible and cost-effective, and may prove to be a useful investigative tool in the diagnosis of anorectal disorders.

Action Potentials

Prognostic implications of normal exercise tomographic thallium images in patients with angiographic evidence of significant coronary artery disease.

This study examines the prognostic implications of normal exercise tomographic thallium images in medically treated patients with angiographic evidence of coronary artery disease (CAD). There were 97 patients aged 60 +/- 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (> or = 50% diameter stenosis). The exercise test was submaximal in 51 patients (53%); ST-segment depression during exercise occurred in 20 patients (21%), and angina during exercise occurred in 23 patients (24%). Most patients (71%) were receiving antianginal therapy. During a mean follow-up of 32 months, only 3 patients had cardiac events: 2 died of cardiac causes and 1 had nonfatal myocardial infarction (event rate 1.1%/year). None of those 3 patients had positive ST response during exercise. Thus, medically treated patients with CAD (including those with multivessel CAD) have a benign prognosis in the presence of normal exercise thallium images. These results have important implications in patient management and cost of health delivery.

Coronary Angiography

The degradation of triazo dye chlorantine fast green BLL in aqueous solutions by gamma radiation--III.

The radiation degradation yield (Gd values) of Chlorantine Fast Green BLL (CFGBLL), Gd, i.e. the value of moles of dye molecules degraded per joule of energy absorbed (sometimes given in units of the number of molecules decomposed per 100 eV of radiation energy absorbed) was measured in aerated, oxygen- and nitrogen-saturated aqueous solutions. The Gd values were found to be 0.063, 0.0715 and 0.033 mumol/J or (0.61, 0.69 and 0.32/100 eV) respectively. The relatively low degradation yield indicates the absence of chain reactions and probably the poor efficiency and economics, in terms of the practical application of the radiation process. For applications in the radiation treatment of waste water, it is noted that in the presence of oxygen and at higher concentration of CFGBLL, the value of Gd increases markedly, so that it may be practical to monitor the extent of sterilization of water. In addition the radiation processing of CFGBLL waste water may also become economically feasible. The specific bimolecular rate constant of the reaction of CFGBLL with the .OH was determined by studying the effect of ethanol concentration on Gd using competition kinetics. This rate constant was found to be k = 2.32 x 10(10) and 1.65 x 10(10) L mol/s at 610 and 380 nm wavelengths, respectively. Suggestions are made for the possible use of CFGBLL aqueous solution as a chemical dosimeter in the range of absorbed dose from 0.1 to 5 kGy.

Azo Compounds