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Biomedical subjects

A Abrahams

Publications and source records attributed to A Abrahams.

5 recordsLinked to original sources

Granulocytic sarcoma of the testis.

Granulocytic sarcoma is a rare tumor composed of neoplastic blood cells, typically occurring during the course of, or before the onset of, acute nonlymphoblastic leukemia. We present a case of a 37-year-old man with acute testicular pain who was found to have a testicular mass diagnosed as granulocytic sarcoma (GS). Because GS virtually always progresses to leukemia, he underwent postoperative radiotherapy and chemotherapy. He was free of disease 6 months after treatment. This case highlights a rare hematologic cancer that urologists and pathologists should be aware of because it can present as a testicular mass.

Adult↗

[Mediagenic psychoses].

Disturbances of psychotic intensity resulting from external trauma at times of crisis and tension have been described in the literature, particularly in combat reactions, including the Saddam syndrome. Acute psychoses as reactions to mystical-religious fervor have also been described. We describe 2 clusters of patients admitted with an acute, delusional, psychotic picture against the background of the Vanunu treason trial and later the strong messianic expectations aroused among the followers of the Rebbe of Lubavitch. Both of these events received extensive coverage in the Israeli press and electronic telecommunication media. The emergence of the mental disturbances and the content of the psychoses were linked to the particularly strident and dramatic media coverage of these 2 events. The impact of the reports of wide-spread messianic fantasies in the contemporary news bulletins on those with preexisting premorbid sensitivity was sufficient to trigger the psychoses. The delusional content was topical, and not that of the traditional psychotic delusions such as that of being Napoleon. This emphasizes that not only an authentic major external trauma such as a war is capable of triggering psychosis, but also emotionladen, stressful news items, frequently repeated in the media (such as reports of espionage or messianic fervor), may have similar effects.

Acute Disease↗

The effect of exposure to positive space charge on aversive responses to noxious stimuli in rats.

Exposure of rats to positive atmospheric ions for four days or longer results in an increase in aversive response times (tail flick and hot-plate). While these effects are similar to those produced after opiate administration, they could not be inhibited by naloxone treatment. Prompt reversal of the positive ion analgesic effect, however was brought about by treatment with parachlorophenylalanine which lowers brain serotonin levels. The data suggest that the action of positive ions on the pain inhibitory system is dependent upon an intact serotonin pathway and that the effects on this system are mediated via central rather than peripheral neural mechanisms.

Analgesia↗