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Biomedical subjects

A Adetuyibi

Publications and source records attributed to A Adetuyibi.

26 records · Page 2Linked to original sources
PubMed1975

Oral hypoglycaemic agents in the management of diabetes mellitus in Nigerians.

Therapy of diabetes mellitus with oral hypoglycaemic agents is reviewed in 445 patients, excluding 18 patients who failed, primarily, to respond to these drugs. The findings are discussed with particular reference to the latent period between the onset of therapy and the observed response. It is probable that the more potent, newer oral hypoglycaemic drugs may help to remove this latent period or reduce its duration.

Adult↗
PubMed1975

Insulin in the management of diabetes mellitus in Nigerians.

Insulin therapy was reviewed in 172 Nigerian diabetic patients. Insulin zinc suspension (IZS--lente) was the preparation most commonly used and therapy was free of side effects. Only a small number of the patients (students) had the problem of unrestricted physical activity and possibly irregular eating habits which might adversely influence insulin therapy. Although in the majority of cases, the age of onset of diabetes mellitus was under 21 years, insulin dependence covered a broad age spectrum. It was not possible to predict the severity of the diabetes from the age of onset. There was about equal chance that therapy might be changed from insulin to oral hypoglycaemic drugs or vice-versa.

Adult↗
PubMedDate not supplied

Insulin--binding antibodies in Nigerian diabetic patients.

The levels of insulin antibodies were determined in 68 diabetic patients on insulin treatment and 30 normal subjects. Fifty (73.5%) of the patients had low levels of insulin antibodies (less than 20%), twelve (17.7%) had moderate levels (between 20 and 40%) while the remaining six (8.8%) had high antibody levels (greater than 40%). There was poor correlation of insulin antibody level with insulin dose (r = 0.16, p less than 0.1) and with duration of disease (r = 0.19, p less than 0.5). Where high levels of antibodies were detected the problems encountered in treating the patients with highly purified insulin preparations are discussed.

Diabetes Mellitus, Type 1↗