[Problems of individual psychology (Alfred Adler)].
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Age Factors↗
Biomedical subjects
A Adler
Publications and source records attributed to A Adler.
Parasitism of monolayer cultures of dog tissue by Histoplasma capsulatum. I. Preliminary investigations.
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Animals↗
Further studies on the thiol groups of human haemoglobin.
When the SH groups of various derivatives of human haemoglobin are converted into their mercuric mercaptides small changes are observed in the optical rotatory dispersion in the range 385-294mmu. These changes are proportionately greater for the reactive than for the unreactive SH groups. These observations have been interpreted in terms of the conformational changes that are likely to occur in the haemoglobin molecule on modification of the SH groups.
Journal Article↗
Office treatment of the chronic schizophrenic patient.
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Humans↗
Regionally selective effects of gonadectomy on cortical catecholamine innervation in adult male rats are most disruptive to afferents in prefrontal cortex.
Changes in gonadal hormones induced early in life produce substantial, seemingly permanent decreases in tyrosine hydroxylase (TH)-immunoreactive axon density in sensory, motor and prefrontal regions in the rat cerebral cortex. Less is known, however, about the responsiveness of cortical catecholamines to hormone stimulation during adulthood. In this study we expanded upon an earlier analysis of the effects of acute (4 day) and chronic (28 day) gonadectomy in adult male rats on TH innervation in right hemifield of the cingulate cortex to include assessment of sensorimotor areas previously examined following perinatal gonadectomy, the left cingulate hemifield, and one additional prefrontal area - the dorsal anterior insular cortex. Qualitative and quantitative analyses of immunoreactivity revealed modest, transient declines in innervation in sensorimotor areas 4 days after gonadectomy, and a return to normal innervation densities by 28 days after surgery. In cingulate and insular cortices, however, strikingly depleted axon densities observed following acute gonadectomy rebounded to significantly higher than normal levels of innervation 3 weeks later. All effects were attenuated in gonadectomized animals supplemented with testosterone. Thus, for cortical catecholamine innervation, as for other endpoints of hormone stimulation, gonadal steroid sensitivity appears to change dramatically with lifestage. In adult male rats, this sensitivity is also marked by a seemingly selective vulnerability of catecholamine innervation in prefrontal areas to changes in the hormone environment induced by gonadectomy.
Afferent Pathways↗
Human platelet antigen gene frequencies in the Austrian population.
Gene frequencies for the human platelet antigen systems HPA-1, -2, -3, and -5 were determined directly from DNA isolated from cord blood of more than 900 randomly selected Caucasoid newborns in Vienna, Austria. Genotyping was performed by specific amplification of the respective regions coding for platelet glycoproteins GP Ib, IIb, IIIa, and Ia by PCR. These PCR products were analyzed after restriction enzyme digestion and electrophoresis. The observed gene frequencies were: HPA-1a: 0.852, HPA-1b: 0.148; HPA-2a: 0.918, HPA-2b: 0.082; HPA-3a: 0.612, HPA-3b: 0.388; HPA-5a: 0.892, HPA-5b: 0.108. There was a good fit with the Hardy-Weinberg equilibrium. Results from serological determinations and genotyping showed no discrepancies.
Antigens, Human Platelet↗
Enumeration of probiotic bacilli spores in animal feed: interlaboratory study.
Fourteen out of 17 laboratories completed an interlaboratory study comparing 2 pretreatment protocols of feed samples containing authorized probiotic bacilli spores. Both methods used tryptone soy agar for enumeration. Pretreatment A involved preparation of a suspension of the feed sample in 50% ethanol. For pretreatment B, the sample was suspended in peptone salt solution and heated at 80 degrees C for 10 min. Each laboratory analyzed 12 samples (6 per pretreatment), which represented duplicates of a high (10(9) colony-forming units [CFU]/g) and low (10(5) CFU/g) level of bacilli spores or a blank that contained vegetative probiotic bacteria only. For pretreatment A, the repeatability relative standard deviation (RSD(r)) was 2.9% for the low level and 2.5% for the high. The reproducibility relative standard deviation (RSDR) values were 7.8 and 5.9%, respectively. Pretreatment B revealed RSD(r) values of 1.1 and 1.0%, and RSDR values of 5.8 and 3.4%, respectively. The heat treatment (pretreatment B) of feed samples had better precision data, resulted in higher viable bacilli counts, and was more effective in deactivating vegetative background flora. It is therefore recommended for adoption for official control purposes and for CEN and ISO standards.
Animal Feed↗
A comparison of student radiographic reject rates.
Educators and administrators often are called upon to estimate the economic considerations of students in radiology departments for clinical education. Yet, little has been written about student radiographic reject rates. This study assessed the radiographic reject rate of 320 first- and second-year students from 21 hospital- and college-sponsored programs in 18 states.
Humans↗
An analysis of radiographic repeat and reject rates.
A literature search of the past 20 years of publications on radiographic repeat/reject rates located 11 reports of 48 studies. A significant unpublished 12th report added a 49th. This article evaluates these studies to propose mean radiographer repeat/reject rates and reasons for economic uses in administrative evaluations. A comprehensive bibliography provides a resource for future repeat rate studies.
Quality Control↗
Outcome of mechanical lithotripsy of bile duct stones in an unselected series of 704 patients.
BACKGROUND/AIMS: This paper evaluates the potential benefit of non mechanical bile duct stone lithotripsy techniques. The efficacy, limitations and risks of mechanical lithotripsy as first choice procedure were studied. MATERIAL AND METHODS: Endoscopic sphincterotomy was performed by Erlangen-type papillotomes, stone extraction by Olympus baskets and mechanical lithotripsy by the Wurbs-system. In an unselected series of 704 patients, everyone with common bile and hepatic duct stones (independent of size, number, location and stone consistency) was included in the study. RESULTS: Complete stone clearance by endoscopic sphincterotomy and basket extraction was possible in 87.6%. Additional mechanical lithotripsy led to a success rate of 98.4% and in combination with ESWL of 98.5%. In 11 patients without possibility of endoscopic stone removal (1.6%), 4 had no access transpapillary (B-II-situs or duodenal diverticulum), 5 anatomical problems (S-shaped common bile duct, intrahepatic stones or impacted stones in cystic duct orifice), and 2 refused further endoscopic interventions. Complication rate was 1.4% (thereof 1.1% successful treatment by endoscopic or surgical means), lethality rate 0.3%. CONCLUSIONS: A very high rate of stone clearance by standard endoscopic procedures is possible. In those patients where mechanical lithotripsy is not successful, other non-surgical lithotriptic procedures either cannot be applied because of anatomical reasons or if performed, the improvement in success rate is marginal.
Cholelithiasis↗
Endoscopic management of biliary complications after orthotopic liver transplantation.
BACKGROUND/AIMS: Biliary complications after orthotopic liver transplantation are still a severe problem and often require a second surgical operation. MATERIAL AND METHODS: In our center we studied 500 patients after liver transplantation. RESULTS: In this patient population, we found 44 patients suffering from diseases of the bile duct system after liver transplantation. Biliary complications were caused by stenoses which were localized most often in the common bile duct of the recipient (65%) but also in the common bile duct of the donor liver (26%) as well as in the anastomosis of common bile duct (9%). In all cases ERC was able to identify location, entity and dimension of the biliary complication thus leading to therapeutic strategy. 66% (27 out of 41) of the patients with biliary complication could be cured definitely by endoscopic methods alone while 29% (12 out of 41) of these patients needed surgical operation and 5% (2 out of 41) received both, endoscopic and surgical therapy. Patients suffering from multiple complications could be cured partially by endoscopic methods improving patient condition for subsequent surgery. Ischemic type biliary lesions of the extrahepatic ducts (ITBL type I) as well as of the intrahepatic ducts (ITBL type II) could be successfully treated by endoscopy. Only rare cases of multiple lesions intra- and extrahepatically due to ITBL type III gave no chance to endoscopy and demanded directly surgical operation. CONCLUSIONS: Our results show that most of the biliary complications after liver transplantation can be resolved by endoscopic treatment.
Biliary Tract Diseases↗
The wide-channel endoscope optimizes the success of emergency endoscopy.
INTRODUCTION: Success of emergency endoscopy in upper GI-hemorrhage for diagnostics and treatment is limited by masses of blood clots, food or both. Using standard endoscopes supported by adjuvant techniques bleeding source can be defined in 90 to 95%. These procedures are often time consuming. Only bleeding sources which are defined can be treated. This is difficult in cases of ongoing hemorrhage. Circulatory shock may occur as well as aspiration of gastric contents. For these reasons we developed the new wide-channel endoscope. METHODS: This endoscope (GIF-XT-30, Olympus, Tokyo) has two channels, one with a diameter of 6 mm and a jet channel with 1 mm. The outer diameter at the distal end is 13.7 mm. A three-way stopcock for suction and water input is connected to the 6 mm channel. RESULTS: We achieved complete evacuation of stomach contents in 122 of 123 patients (= 23% of all emergency patients in this series) with upper GI-bleeding, in whom complete gastric cleaning and identification of the bleeding source had proved impossible using standard endoscopes. Gastric emptying using the big channel endoscope was possible within 5 minutes in all successful cases. Optimal conditions for therapeutic procedures were therefore provided. CONCLUSIONS: The possibilities of this instrument enable a more aggressive technique of moving fixed coagula from ulcers to localize the vessel that is to be treated. Even in cases of provoked severe Forrest I A hemorrhage permanent visual control can be achieved. It is an indispensable tool for major endoscopic centers in emergency situations.
Adult↗