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Biomedical subjects

A Afonso

Publications and source records attributed to A Afonso.

3 recordsLinked to original sources

[Myxedema coma].

Five patients, 4 female and 1 male, aged 45 to 73, were observed in myxedema coma between 1984 and 1992. In three patients hypothyroidism was not known. Depressed consciousness, hypothermia, bradycardia and no goiter were common to all and a precipitating factor could be identified in 3 of them. Therapy included L-thyroxine and/or triiodothyronine by nasogastric tube, hydrocortisone and supportive measures. Outcome was good in the 2 patients with known precipitating event, less impaired consciousness and normalization of body temperature by the third day of treatment.

Aged

[Hyperthyroidism caused by non-neoplastic inappropriate TSH secretion].

We report a case of hyperthyroidism due to non-neoplastic inappropriate thyrotrophin secretion in a 31 year old woman. Increased T3 and THS levels after thyroidectomy led us to suspect the diagnose. Serum levels were further increased by TRH and only partially suppressed by triiodothyronine and computerised axial tomography showed a normal sellar region. These features are characteristic of inappropriate TSH secretion due to thyrotroph resistance to thyroid hormones. Bromocriptine and octreotide were ineffective in lowering TSH levels. Pregnancy and breastfeeding postponed 3,5,3'-triiodothyroacetic acid therapy.

Adult

[Prevention of alveolar bone resorption with the use of hydroxyapatite granules].

The authors describe in review the alveolar absorption according to bone physiology, and the absorption prevention using hydroxylapatite. Finally it is pointed the good preliminary results in a 30 patients study during 8 months using hydroxylapatite (OSTEOPATITE) and plaster particles in alveolar absorption prevention.

Alveolar Bone Loss