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Biomedical subjects

A Agertoft

Publications and source records attributed to A Agertoft.

4 recordsLinked to original sources

[Infantile myofibromatosis. A case of solitary type in a 6 months old male].

A case of infantile myofibromatosis in solitary form occurring in Denmark is presented. The tumour was situated in the right inguinal region and had resulted in occlusion of the femoral vein and involvement of the lymph glands. The diagnosis is established histologically by demonstration of noduli of cells resembling myofibroblasts arranged in bundles and fasciculi. Once the diagnosis is established an expectant attitude may normally be assumed.

Groin

[Fetal hydronephrosis].

Antental intervention in cases where the foetus was suspected of having hydronephrosis has been the subject of intense discussion in recent years where the diagnosis was technically possible. The object of this investigation was to assess the end result in foetuses with hydronephrosis diagnosed prenatally and who were treated expectantly without intervention in utero. Fourteen consecutive cases of suspected foetal hydronephrosis are described. In four of the cases the hydronephrosis was transient without consequences for subsequent renal function. Three infants died, however, immediately after birth. All three were shown to have multiple malformations and/or chromosome anomalies. Unilateral dilatation of the upper urinary tract (seven cases) was by and large, associated with a good prognosis. Foetuses with bilateral dilatation of the upper urinary tract (seven cases) had poorer prognoses but this might also be related to other serious malformations. If this is compared with the disappointing result obtained by prenatal intervention in the form of foetal surgery or introduction of vesico-amniotic stents, very little evidence is found in favour of in utero intervention. In the great majority of cases, conservative prenatal regime is preferable.

Abnormalities, Multiple

Intestinal perforation in a two-year-old child with eosinophilic gastroenteritis.

A two-year-old boy underwent a laparatomy for an intestinal perforation due to eosinophilic gastroenteritis. He had marked peripheral blood eosinophilia and a small duodenal biopsy showed heavy eosinophilic infiltration in the mucosa. After 1 1/2 year on a restricted diet, a control duodenal biopsy showed only slight eosinophilia. Perforation of the small intestine is a rare but serious complication in eosinophilic gastroenteritis.

Child, Preschool

[Scheuermann's disease].

Scheuermann's disease is most frequently diagnosed in patients between 13 and 17 years and is subdivided into high, long and low kyphoses. The symptoms consist of pain which may be aggravated by physical exertion. Pain is most frequent and most severe in the long and low kyphoses. The etiology and pathogenesis are not entirely elucidated but it is probable that there is a genetic component, that the condition is not unifactorial and that it may be due to weakness in the epiphyseal plates of the vertebrae. Radiography reveals irregularities of the end-plates of the vertebrae, frequently with Schmorl's impressions, narrowing of the intervertebral spaces, one or more wedge-shaped vertebral bodies and increased kyphosing. No effective symptomatic treatment is known but the patients should be advised about choice of career and work. In order to avoid hyperkyphosis and chronic pain, back and abdominal musculature must be strengthened and mobility in the spine improved. Gymnastics, swimming and cycling on stationary bicycles may be recommended but sports associated with jumping and marked stress for the spine must be warned against. In few and severe cases, treatment with a corset or operation may be necessary.

Adolescent