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Biomedical subjects

A Agustí-Vidal

Publications and source records attributed to A Agustí-Vidal.

34 records · Page 2Linked to original sources
PubMed1986

Correlation of bronchoalveolar lavage and clinical and functional findings in asbestosis.

Respiratory clinical, radiographic, and functional findings were assessed and correlated with bronchoalveolar lavage (BAL) cellular changes in 52 asbestos workers (27 with and 25 without asbestosis) and in 15 control subjects without asbestos exposure. Subjects with asbestosis had a moderate neutrophilic alveolitis (7.8 +/- 5%) compared with the other groups (p less than 0.001) that was correlated with the presence of crackles (p = 0.03) and PaO2 (p less than 0.05) and AaPO2 at rest (p less than 0.05) values. Asbestos bodies (AB) in BAL were quantitated in 34 of the 52 asbestos workers (21 with and 13 without asbestosis) and in the control group. They were present in 83% of asbestos workers but they were absent in the latter. No significant differences were observed in the number of AB between those asbestos workers with and without lung disease. We conclude that crackles on auscultation and PaO2 and AaPO2 values may well be good indicators of the staging of neutrophilic alveolitis in asbestosis. In contrast, the amount of AB in BAL is not a reliable marker of asbestos lung fibrosis.

Adult↗
PubMed1985

Subconjunctival haemorrhage: a feature of acute severe asthma.

Bilateral subconjunctival haemorrhage was observed on 5 separate occasions in 4 patients presenting a fulminant form of acute severe asthma. Four of these episodes required ventilatory support. All patients recovered from their asthma attack after treatment with bronchodilators, corticosteroids, and oxygen. The incidence of this previously unreported finding represents 5% of the total number of patients with acute severe asthma mechanically ventilated in our intensive care unit from 1976.

Adult↗
PubMed1983

Acute respiratory failure and tracheal obstruction in patients with intrathoracic goiter.

Four cases of acute life-threatening tracheal obstruction due to intrathoracic goiter are reported. Acute respiratory insufficiency caused by an upper airway obstruction in patients with intrathoracic goiter is exceptional. In 3 of 4 cases reported, the histologic study showed multiple foci of recent hemorrhage, the mechanism probably responsible for these episodes.

Adult↗
PubMed1983

Laryngotracheal injury due to endotracheal intubation: incidence, evolution, and predisposing factors. A prospective long-term study.

The purpose of this study was to assess the incidence, evolution and long-term effects of laryngotracheal lesions due to endotracheal intubation and to evaluate the import of factors in the genesis of laryngotracheal injury. Over a 12-month period, we performed fiberoptic bronchoscopy (FBS) in 19 critically ill patients with endotracheal intubation. Early laryngeal lesions, mainly true vocal cord granulomas and ulceration, appeared in 12 (63%) patients and were resolved by the 3rd month in all but 3 patients. In 6 (31%) patients, early tracheal lesions appeared in the form of ring-shaped tracheitis at the cuff level and granulomas at the tube-tip level; in 2 (10%) patients, an established tracheal stenosis developed and early detected ring-shaped tracheitis preceded circumferential fibrous stenosis. Severe respiratory failure, high cuff pressure, and secretion infection showed a statistical correlation to tracheal injury.

Adult↗
PubMed1983

Mechanical ventilation in severe exacerbation of asthma. Study of 26 cases with six deaths.

A prospective study was carried out in 26 patients intubated and mechanically ventilated for severe exacerbation of asthma. The age of onset of asthma and the duration of disease showed wide variations, but most of the patients were women in their fifties with chronic asthma. However, 23% had the more benign intermittent course. Most patients had a prodromal period of several days with progressive deterioration. Eight patients developed sudden attacks, in three of them aspirin-intolerance was responsible, in two patients emotional disturbances could play some role as triggering factors, and in three other patients no obvious reason was found. Identification of factors responsible for the sudden attacks may be relevant to the management of these severe cases. The majority of patients were intubated immediately on arrival or during the first hours after admission. Deaths were related to complications produced by hypoxia, or hospitalization in an intensive care unit. Probably many of these patients would not have died if an appropriate steroid treatment had been given some days before.

Adolescent↗