Biomedical subjects

A Aharoni

Publications and source records attributed to A Aharoni.

39 records · Page 3Linked to original sources

PubMedDate not supplied

Prolactin response to electroconvulsive shock in anesthetized rats.

Serum prolactin level (SPL) of anesthetized rats was measured in response to electroconvulsive shock (ECS). This measurement served as an indicator of dopaminergic and serotonergic activity. Such neurotransmitter activity was modulated by pretreatment with cyproheptadine, parachlorophenylalanine (PCPA), pimozide, bromocriptine or L-dopa. A statistically significant lowered SPL was found in rats given ECS plus antiserotonergic agents, in comparison with animals receiving antiserotonergic agent or ECS alone. When ECS was administered to rats pretreated with the dopaminergic blocker, pimozide, there was a significant decrease in SPL, compared with animals receiving pimozide alone. When the dopaminergic system was stimulated by dopamine agonists, there was no elevation of SPL in response to ECS. Thus, there may be a balance between serotonergic and dopaminergic systems. The agents used in the experiment may upset this balance and produce a change in prolactin response to a given ECT stimulus.

Animals↗

PubMedDate not supplied

Postpartum maternal group B streptococcal meningitis.

Maternal group B streptococcal (GBS) meningitis is rare, with only four cases previously reported in the literature. In this review a fifth case of postpartum GBS meningitis is presented. The five cases are compared with 34 cases of GBS meningitis in nonparturient adults. All cases of maternal GBS meningitis followed a vaginal delivery. The mean age of patients who had GBS meningitis outside the perinatal setting was 55 years, and most of these individuals had associated illnesses or frank immunosuppression; the mortality rate in this group was 23%. In contrast, all five patients with maternal GBS meningitis recovered. The case presented herein, like the four previous cases, illustrates the point that when patients with maternal GBS meningitis are treated immediately and have been healthy before the infection, the prognosis is good.

Adult↗

PubMedDate not supplied

Cervical cerclage in uterine malformations.

This retrospective study represents our experience with cervical cerclage (suture) in pregnancies with uterine malformation. Seventeen patients with uterine malformations were involved. In these patients, the outcome of 31 gestations with cervical cerclage was evaluated. Uterine malformation was associated with cervical incompetence in 41% of the patients. Term delivery rate and fetal loss were observed in 56% and 26% of pregnancies, respectively. Infant salvage was not significantly different regardless of whether cervical incompetence was present or absent. A prolonged hospital stay and frequent use of tocolysis were noted during gestations with cerclage. Our data suggest that the outcome of pregnancies with uterine malformation was not improved by cervical cerclage when the indication for cerclage was the malformation itself.

Adult↗