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Biomedical subjects

A Alexandre

Publications and source records attributed to A Alexandre.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

Recognition memory alterations after severe head injury. Preliminary results in a series of 50 patients.

The Authors report a study on recognition memory in a series of 50 severe head injuries. The effect of cerebral trauma is expressed by reduction in recognition memory and in learning. A significant difference is found between frontal lesions and temporal lesions. Left temporal lobe damage causes a more severe deficit than right temporal lobe damage. Extradural and subdural haematomas cause no such severe deficit. Neurological syndrome of level of lesion significantly correlates with the performance. PTA duration shows no relation.

Adult↗
PubMedDate not supplied

Stereotactic exploration of deep-seated or surgically unamenable intracranial space-occupying lesions.

Stereotactic biopsy of surgically unamenable intracranial lesions has been performed in our Neurosurgical Division since 1977. Riechert's apparatus is employed. An originally developed biopsy instrument and its advantages are described. Stereotactic coordinates of the biopsy site are found by CT scanner data using the technique described earlier by us. The series consists of 20 patients in whom a variable number of biopsy samples (from 1 to 5) was taken. Mortality and morbidity were nil. In 2 cases the stereotactic exploration led to a therapeutic maneuver: a cystic craniopharingioma and a cerebellar hematoma were extirpated. The clinical, neurological and histological features of 5 paradigmatic cases are illustrated. The relevance of histological diagnosis for adequate treatment is stressed. The indications for this surgical procedure are discussed.

Adult↗
PubMedDate not supplied

Posterior rhizotomies for spasticity in children affected by cerebral palsy.

The Authors report their experience on the surgical treatment of spastic syndromes in children affected by cerebral palsy. The series consists of 21 patients: the mean age is 9.3 years. In 18 patients in whom the clinical picture showed spastic paraparesis a posterior selective lumbar rhizotomy was performed: 3 patients with disabling spastic tetraparesis underwent posterior cervical C1-C3 rhizotomy. The follow-up ranges from 4 months to 3 1/2 years. No mortality nor major complications were observed in the entire series. Clinical results can be considered good on the whole; they are related to the motivation to the movement, perceptive deficits, intellectual impairment.

Adolescent↗
PubMedDate not supplied

Breathing alterations in head injured patients.

Breathing abnormalities in patients affected by acute cerebral damage are herein studied as neurological signs of localizing value for the neurological diagnosis of the level of the lesion. Incidence and types of abnormal breathing pattern correlate with neurological syndromes, and in a given neurological syndrome the presence of these alterations entails a more severe outcome. Tachypnea shows the most significant correlations from a diagnostic and prognostic point of view.

Ataxia↗
PubMedDate not supplied

The influence of the administration of pyritinol on the clinical course of traumatic coma.

(1) In a total of 100 patients with traumatic coma who were admitted to the intensive care unit of our Department of Neurosurgery we examined the effect of Encephabol after intravenous administration. (2) Compared to patients with the same clinico-neurological conditions who were, however, not treated with Encephabol, the cases treated by the preparation did not show any significant clinical improvement. Moreover, in the Encephabol group mortality rate in patients with an unfavourable prognosis sank to 35.3% (mortality rate in the comparative group: 54.2%). (3) Untoward effects on the clinico-neurological condition, cortical electrogenesis, vegetative functions and body fluid parameters were not observed after administration of the preparation.

Adolescent↗