PubMed Health⌕ Search

Biomedical subjects

A Alfaro

Publications and source records attributed to A Alfaro.

At least 19 recordsLinked to original sources
PubMed1992

Idiopathic trigeminal sensory neuropathy.

Idiopathic trigeminal sensory neuropathy is a rare disorder characterized by transient sensory disturbances in the territory of one or more branches of the trigeminal nerve. Acute and chronic forms of the disease have been recognized, but the boundaries between these groups are not clearly defined. Six cases of idiopathic trigeminal sensory neuropathy are reported. All patients presented with sensory abnormalities limited to the territory of one trigeminal nerve, in the absence of other clinical features. The symptoms were on the left side of the face in five cases and on the right side in one. No bilateral involvement was seen. There were no cases of muscle weakness, and the corneal reflex was always present. In two cases, sensory disturbances began in the tongue or lips and later spread through the entire territory of the three trigeminal branches. Both patients recovered completely after 3 months. The other four patients had involvement of the second and third branches (two cases), or the third branch alone (two cases), and the symptoms persisted unmodified for 2 to 4 years. There were no clinical variables at onset to enable one to predict an acute or chronic evolution of the disease.

Adult↗
PubMed1991

[Mumps encephalitis in adulthood].

Mumps virus is one of the most common causes of viral meningitis. Although brain involvement has been observed in a low proportion of children with mumps meningitis, a pure form of mumps encephalitis is extremely uncommon in the adult. A 23 year-old man presented with a rapidly evolving syndrome of cephalalgia , vomiting, mutism, disorders of gait, somnolence and dystonic movements. The electroencephalogram showed a diffusely slowed background activity. The CSF contained no cells, but the total protein concentration was elevated. The patient recovered without sequelae, but severe intellectual and motor disturbances persisted during more than a month. Serological studies showed an increase of blood IgM mumps-specific antibodies. We conclude that mumps encephalitis, although infrequent, should be considered among viral diseases that mimic herpes simplex encephalitis in the adulthood.

Adult↗
PubMed1983

Impaired coronary flow and ventricular function in hearts of hypertensive rats.

Hearts of rats made hypertensive (BP greater than 150 mmHg) by left renal artery clipping and sham operated controls were studied in two series of experiments. In series I, cardiac function was studied in an isolated working heart apparatus at weeks 4, 9 to 10 and 16 to 17 post-surgery. In series II, coronary flow was studied during normoxic and anoxic retrograde perfusions at days 6 to 9 and at weeks 4 and 10 post-surgery. In series I, when compared with controls, hypertensives had lower body weights at weeks 4 and 9 to 10, and higher left ventricular weights at each period. Heart function was depressed for hypertensives when compared with controls as measured by lower stroke volume, peak left ventricular systolic pressure, stroke work, ejection fraction, positive dP/dt, peak aortic flow, and maximal flow acceleration. Relaxation rate as measured by negative dP/dt was also depressed. Hearts from hypertensives had significantly lower coronary flows and MVO2, and increased percent oxygen extraction and effluent lactate/pyruvate ratios. LVEDP was significantly elevated for hypertensives, when LVEDV (ml) was similar for hypertensives and controls. Myocardial actomyosin ATPase activity was depressed for hypertensives at weeks 9 to 10 and 16 to 17 post-surgery. In series II, when hearts were perfused retrogradely, coronary flow was lower for hypertensives than for controls during normoxia at days 6 to 9 and at week 4, and during anoxia at all time periods. The findings demonstrate that impaired coronary vascular reserve develops within days of the development of hypertension in rats, and this can be associated with impaired ventricular function.

Animals↗
PubMed1980

The Skoog rhinoplasty: a modified technique.

This study is a 6-year experience with 305 cases in which the technique was used for large noses. The techniques described is based on the Skoog rhinoplasty principle: autografting the osteocartilagineous nasal dorsum after its reduction to the best suitable shape and size, so that the osseous part of the graft lies on the remaining nasal bones. The authors have conjointly used the intracartilaginous approach, which leaves a unique scar away from the graft, and the extramucosal dissection, which keeps the graft separated from the nasal cavity by an intact mucosal lining. They also used the internal lateral osteotomy, which reduces postoperative swelling. The technique is described with all details. The cases shown demonstrate that this type of rhinoplasty prevents the middle third retraction because of the osteocartilaginous graft and most of the common secondary deformities. The analysis of results obtained in this series show 89 percent excellent (patient and surgeon pleased). Secondary correction had to be done in eight cases, by reducing or removing the graft.

Adult↗