Biomedical subjects

A Alonso Rodrigo

Publications and source records attributed to A Alonso Rodrigo.

14 recordsLinked to original sources

PubMed2001

[Value of a second transurethral resection in the assessment and treatment of patients with bladder tumor].

OBJECTIVE: To analyse the value of a second transurethral resection, repeated within 3 to 6 weeks after the initial resection, in the treatment and the classification of patients with bladder tumour. MATERIAL AND METHODS: We analyse the results of 72 repeated transurethral resection in 23 (32%) patients with T1 G1-2 bladder tumor, 9 (12.5%) with T1 G3 tumor, 31 (43%) with T2a G2-3 tumor and 9 (12.5%) with T2b G2-3 tumor. The evaluated patients are not associated with CIS. RESULTS: Of all 23 T1 G1-2 tumors, 13 (57%) had residual Ta T1 tumor and 1 (4%) T2 tumor. In this group, the second resection changed the treatment in 1 (4%) patient. Of all 9 T1 G3 tumors, 4 (44%) had residual T1 tumor and 1 (11%) T2 tumor. In this group the second resection changed the treatment in 1 (11%) patient. Of all 31 T2a G2-3 tumors, 5 (16%) had residual T1 tumor, 4 (13%) T2 tumor and 6 (19%) T3-T4 tumor. In this group, the second resection changed the treatment in 10 (32%) patient. Of all 9 T2b G2-3 tumors, 2 (22%) had residual T1 tumor, 1 (11%) T2 tumor and 2 (22%) T3-T4 tumor. In this group, the second resection changed the treatment in 3 (33%) patients. CONCLUSIONS: In T1 G1-2 and T1 G3 tumors, a second transurethral resection detect residual tumor in 36% of patients and change the treatment in 6% of patients. In T2a-b tumors, a second transurethral resection detect residual tumor in 50% of patients and change the treatment in 33% of patients.

Adult↗

PubMed2000

[Metachronous tumors of the upper urinary tract following primary superficial tumors of the bladder].

OBJECTIVE: To evaluate the long term incidence of upper urinary tract tumours in patients with surface tumours of the bladder. MATERIAL AND METHODS: Analysis of 78 patients with primary tumour of the bladder pTa-pTl diagnosed between 1978 and 1988. These patients were followed for up to 10 to 21 years (mean follow-up 13.4 years) and were treated with transurethral resection and a variety of endovesical cytostatic agents. RESULTS: Of all 78 patients, 9 (11%) developed an upper urinary tract tumour over an average of 9 years (range 4-18); 2 in the first 5 years, 4 between 5 to 10 years, and 3 between 10 and 18 years. The likelihood of finding a tumour in the upper tract if all 20-year old patients were to be followed would be 25.6% (Kaplan-Meier's method). A high percentage of all upper urinary tract tumours are infiltrant, but the cause of death in 44% of these patients is progression of the tumour of the bladder. CONCLUSIONS: The percentage of tumours of the upper urinary tract that become metachronic following a tumour of the bladder, increases with the duration of the follow-up. A high percentage of these cases are already in high stages when diagnosed. It would be convenient to monitor the upper urinary tract with the same periodicity than the bladder in order to establish early diagnoses. These patients show a high mortality rate, in most cases secondary to progression of the tumour of the bladder.

Adult↗

PubMed2000

[Bilateral testicular luxation].

Contribution of a case report of long-standing bilateral testicular luxation, the result of scrotal trauma caused by a soccer ball. Good aesthetic, endocrine and exocrine results were obtained with surgical treatment. Androgenic hormonal profile and spermiogram performed at six months showed values within the normal range.

Adult↗

PubMed2000

[Abdominal-pelvic actinomycosis with urinary tract involvement, secondary to gynecologic infection caused by intrauterine device].

Abdomino-pelvic actinomycosis is a condition caused by Actinomyces israelii, a Gram-positive opportunistic bacteria that triggers and develops the infection only in previously injured tissues, and then slowly progresses and spreads until it extrinsically affects the urinary tract. Use of an intrauterine device is a known risk factor to suffer from this disease. Relative risk in IUD users is two- to four-fold higher compared to IUD non-users. Risk increased with prolonged IUD use. Treatment is by removal of the causative agent, surgical resection of necrotic tissues and administration of intravenous Penicillin G, 4 million units every 4 hours for 30 days, followed by Amoxicillin 500 mg every 8 hours for 12 months. This paper contributes two cases of abdomino-pelvic actinomycosis with urinary tract involvement in IUD users. Standard treatment was employed with good evolution.

Actinomycosis↗

PubMed2000

[Leiomyoma of the female urethra].

Leiomyoma of the female urethra is a benign mesenchymal tumour highly infrequent in the clinical practice. There is controversy as to its degree of oestrogen hormone dependency and its diagnosis is reached only after pathohistological study of the resection specimen. This type of tumour has excellent prognosis, with few tumoral relapses and no case of malignant transformation having been reported for the time being. Contribution of one case report of leiomyoma of the female urethra with typical clinical-epidemiological features but very uncommon from a topographic insight, as it was located in the anterior side of the distal urethra.

Female↗

PubMed1999

[Metastatic prostate adenocarcinoma in hernial sac. Contribution of one case].

Presentation of a case of stage D2 prostatic adenocarcinoma, diagnosed through a chance finding of micrometastasis in the pathohistological study of the hernial sac of a patient undergoing inguinal herniorrhaphy. Most usual sites for prostate cancer metastasis are lymph nodes, bones, lungs, liver, and brain. During our revision of unusual anatomical sites for prostatic carcinoma metastasis, we found references of metastasis on the uvea, larynx, orbit and maxillary sinus. The peritoneal cavity was not found to be a common site for metastatic implants. It was also found that such peritoneal spread was usually diagnosed after a postmortem examination.

Adenocarcinoma↗

PubMed1999

[Value of non-contrast helical computerized tomography in nephrotic colic assessment].

OBJECTIVE: To compare non-contrast helicoid CAT to urological ultrasound in order to determine the sensitivity of both in the etiological diagnosis of nephritic colic. MATERIAL AND METHODS: Retrospective study conducted on a total of 86 patients seen in our ER service over a 12-month period with a diagnosis of nephritic colic. All patients with suspicious diagnosis of nephritic colic underwent X-ray examination, with either non-contrast helicoid CAR or urological ultrasound, or with a combination of both imaging techniques. Radiologic diagnosis of nephritic colic was made by direct visualization of the obstructive cause or by the presence of indirect radiological signs of upper urinary tract obstruction. RESULTS: Of 86 patients studied, in 84 (97.67%) a urinary stone was the cause for obstruction. Overall sensitivity of helicoid CAT to diagnose colic etiology was 94.73%, whereas ultrasound sensitivity was only 53.42%, displaying a particularly low sensitivity when the obstruction was located at the mid third level of the ureter. CONCLUSIONS: Non-contrast helicoid CAT shows superior sensitivity as a radiologic technique than ultrasound to identify the cause of a nephritic colic in any segment of the upper urinary tract.

Adult↗

PubMed1999

[A massive hernia of the bladder into the scrotum. A report of a case].

The hernia of the bladder in the scrotum is a highly uncommon observation. From the clinical standpoint the usual manifestation is a two-stroke voiding. The recommended urological examinations to reach a diagnosis are ultrasound, endovenous urography, retrograde urethrocystography and cystoscopy. Management includes the de-obstruction of the lower urinary tract, if present, resection of associated peritoneum, resection or reduction of the vesical hernia and repairment of inguinal path. The case contributed corresponds to a vesical hernia in a 72-year-old patient, with no obstructive cause, that was treated surgically by resection of the herniated bladder, with good morphological and functional results.

Aged↗

PubMed1998

[Superficial cancer of the bladder: which controls should follow and for how long the free of tumor patients?].

OBJECTIVES: To answer the following question: what monitoring and for how long should be maintained in patients with Ta-T1 vesical neoplasia and no tumoral relapse? MATERIAL AND METHOD: Analysis of relapse probabilities in 123 patients with Ta-T1G1G2G3 primary tumours who had not relapsed for at least three years of follow up after transurethral resection. All patients were treated between January 1976 and December 1986; they all have follow-up potential of over 10 years. Mean follow-up 8.1 years, minimum 4 years, maximum 18 years. RESULTS: Probabilities of relapse at 3 to 5 years, 6 to 10 years, 11 to 18 years are 18%%, 24% and 13%, respectively. Relapses were superficial in 38 cases (90%), infiltrant in 4 (10%) G1 in 21 (50%), G2 in 12 (29%), G3 in 9 (9%), single in 33 (79%), multiple in 9 (21%), under 2 cm in 35 (83%), over 2 cm in 7 (17%). CONCLUSIONS: Epidemiologically, individuals with a background of surface vesical tumour have a much higher risk of relapse than the Spanish normal population and therefore they should be monitored for life. Relapses are usually superficial, low grade, single and small in size. Cystoscopy is the monitoring technique offering more possibilities for detection.

Adult↗

PubMed1996

[Prevention of superficial bladder cancer with mitomycin C or interferon: final results of a prospective study].

OBJECTIVES: Herein we present the final results of a prospective randomized study comparing two prophylactic treatment modalities for superficial bladder tumors: chemotherapy with mitomycin C and immunotherapy with interferon. METHODS: The study comprised 65 patients. Mitomycin C was utilized in 34 and interferon in 31 patients. RESULTS: The mitomycin C-treated patients had 41% recurrence, 1.7 recurrence/100 patients-month, 17 months mean time to recurrence and 8.8% tumor progression. The patients receiving interferon had 45% recurrence, 2.4 recurrence/100 patients-month, 12 months mean time to recurrence and 22.2% tumor progression rate. No significant differences were observed between the two groups of patients. Treatment was well-tolerated by both groups and the cost:efficacy ratio was higher for the interferon-treated patients. CONCLUSIONS: Immunoprophylaxis with interferon is as effective, but costs more than chemoprophylaxis with mitomycin C. Both agents have a moderate effect relative to control of recurrence, time to recurrence and tumor progression.

Adult↗

PubMedDate not supplied

[Bladder leiomyoma].

OBJECTIVE: Mesenchymal benign tumours of the urinary bladder are rare and account for 1%-5% of all bladder tumours. The leiomyoma is the most common and constitute 46.6% of this group. 25 cases have been described in the national literature. We report an additional case of leiomyoma of the bladder. CASE REPORT: A 53 year-old man with a chronic history of urinary frequency and microscopic hematuria. Physical examination was normal. An excretory urography demonstrated a filling defect in the right bladder wall. The cystoscopy confirmed the tumour, covered with normal bladder mucosa. The echography showed a solid tumour. A computerised tomography scan and magnetic resonance showed a sessile lesion in the right bladder wall with low-intermediate intensity signal and with normal signal of muscle, mucosa and perivesical fat. The clinical diagnosis was leiomyoma of the bladder. Partial cystectomy was done and the histological diagnosis confirmed the clinical diagnosis. CONCLUSIONS: The leiomyoma of the bladder is a rare tumour however it should be considered in the differential diagnosis before surgical treatment.

Humans↗

PubMedDate not supplied

[Extragonadal germ cell tumor with "burned-out" phenomenon in the testis].

The "burned-out" phenomenon in germ-cell neoplasias is defined by the presence of an extragonadal germ-cell tumour with no tumour at the testis level where a series of distinctive histological lesions can be detected indicative of the earlier presence of an already disappeared testicle tumoration. Extragonadal germ-cell tumours with "burned-out" phenomenon show better evolution than their primary counterparts and are treated similarly to primary tumours of the testis. Currently, in the presence of retroperitoneal tumoration, a scrotal ultrasound study with high frequency transducers can lead to a suspected picture of tumoral involution. This paper contributes one retroperitoneal seminoma with "burned-out" phenomenon in the homolateral testis in a 35-year old patient. Available clinical and radiological criteria were enough to reach a suspected diagnosis. Homolateral orchiectomy and biopsy of retroperitoneal tumoration were performed, rounding treatment up with polychemotherapy. Evolution was good with immediate complete response.

Adult↗

PubMedDate not supplied

[Bladder endometriosis].

Endometriosis is the ectopic location of the endometrium. It is quite unusual to find endometrium foci within the vesical cavity, this experience representing only 1-2% of all possible locations. This paper contributes one vesical endometriosis in a 35 year old woman endoscopically diagnosed because of a solid tumour with surface bluish bullae or cysts. We used Gestrima, in dosage of 2.5 mg twice weekly, as adjuvant treatment to endoscopic surgery with complete objective response.

Adult↗

PubMedDate not supplied

[Analysis of 88 adenocarcinomas of the kidney: evolution of diagnosis and prognosis].

Over the last decade, the evolution in the methods for imaging diagnosis incorporated to the clinical routine, has contributed to improve the prognosis of renal adenocarcinoma by making available an early diagnosis. Eighty-eight kidney tumours, of which 36 were diagnosed and treated between January 1976 and December 1984, and the other 52 between January 1985 and December 1992 are analyzed. The percentage of accidental diagnoses shifted from 8% to 29%. Decreased number of tumours diagnosed by their metastasis, from 22% to 6%. Increased percentage of cases diagnosed in early stages P1-P2, from 23% to 46%.

Adenocarcinoma↗