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A Alperovich

Publications and source records attributed to A Alperovich.

2 recordsLinked to original sources
PubMed1995

Marked PR interval prolongation simulating ST-segment elevation during exercise testing. A case report.

ST-segment elevation during exercise testing is usually indicative of severe proximal coronary artery disease. In this report, the authors describe a patient who underwent exercise stress testing and developed apparent ST elevation in the inferolateral leads. However, noninvasive imaging studies revealed no evidence of myocardial ischemia or other recognized causes of this exercise electrocardiographic (ECG) finding. Analysis of the ECG tracings showed that ST elevation was produced by marked prolongation of the PR interval, super-imposing the P wave on the J-junction of the preceding QRS-ST-segment complex. The authors suggest that marked PR prolongation during exercise may mimic ST elevation, and this possibility should be considered in patients with this exercise ECG finding in whom cardiac evaluation is negative.

Aged↗
PubMed1986

T.I.A. revisited: new wine--old bottle.

TIA has been accepted as a concept of transient cerebral ischemia. There is an ever enlarging body of literature sparking controversies considering its natural history, prognosis, outcomes of clinical trials and usefulness of the concept. Much of the controversy is related to the diverse pathophysiology of TIAs, the selection of patients for clinical trials and the associated risk factor in the studied population. The advantages of the concept are a warning of the possibility of future irreversible pathology an opportunity to treat and/or remove risk factors an opportunity to establish a basis for monitoring the patient and making interim decisions concerning intervention. The risks of the concept are: administering a specific therapy to all patients, failure to fully evaluate the patient once the diagnosis is made, tendency to rely on "experts" for guidance. TIA is a useful concept if one recognizes: the pathophysiology is polymorphous and multiplex, the concept is a signal for diligent search for the underlying cause or causes, it is more important to treat the risk factors than to give a specific therapy.

Anticoagulants↗