Biomedical subjects

A Alvarado Duran

Publications and source records attributed to A Alvarado Duran.

13 recordsLinked to original sources

PubMed1996

[Ethical and legal considerations on assisted human reproduction in Mexico].

Assisted Human Reproduction (AHR) has been one of the most important advances in Ginecology and Obstetrics technology, it has contributed to improve understanding on deeper biological mechanisms of human reproduction. Since Louise Brown's birth, in 1978, in vitro fertilization and Human Embryos Transference (HET) developed by Steptoe and Edwards, became the basis for new AHR methods. Later, writen information has increased, so, it is easy to find a lot of scientific reports in national and international specialized journals. These reports contents not only technological advances, but a lot of ethical thoughts which had showed the necessity for a worldwide legislation.

Cryopreservation↗

PubMed1994

[Endometrial aspiration biopsy].

The factuality and diagnostic accuracy of aspiration endometrial biopsy with Karman's cannula, as compared with the curetted sample with Novak's cannula, were evaluated. Two hundred and thirty endometrial biopsies, were taken, as part of the study in women with fertility problems, at the Assisted Reproduction Clinic and Sterility Clinic, Instituto Nacional de Perinatología. The samples taken with Karman's cannula, Group I (n = 115); and with Novak's cannula, Group II (n = 115), were compared: procedure's time, pain intensity, quantity and quality of samples, macro and microscopically. In 92.2% of group I, tissue adequate for diagnosis, was obtained, as compared with 84.4% in Group II; likewise, the sample was better quantitatively and qualitatively, in Group I; and required time was less than one minute in 90% in Group I, an 83% in Group II. With the use of Karman's cannula, 20% of the patients had no pain, and 0.9% with the use of Novak's cannula. So, it can be concluded that endometrial aspiration with Karman's is reasonable and reliable in the functional histological diagnosis; it permits the obtention of adequate samples, in quantity and quality, and offering as advantages less pain and more security for the patients.

Adult↗

PubMed1993

[Biological process in patients having been impregnated through GIFT or IVF-ET. Clinical experience].

There were analyzed in a retrospective way the results of pre-retrieval hormonal levels as well as the number of retrieved oocytes, mature oocytes and transferred embryos in three groups of patients (2 GIFT, 1 IVF-ET) which achieved a pregnancy, and were matched with groups with no pregnancy. There were no statistically significant differences in most of the analyzed parameters, by the aforementioned we can suppose that pregnancy depends of endometrial quality and in this moment we are not able to modify it satisfactorily.

Adult↗

PubMed1992

[Quantification of deoxyribonucleic acid and collagen as biological markers in uterine leiomyoma].

The uterine leiomyomas (UL) are tumors compound by smooth muscle connective tissue. Growth depends mainly of two basic mechanisms: hypertrophy of myometrial cells and connective tissue deposit. The quantification of the basic elements of the tumor permits to try its application as biochemical markers of disease, auxiliary diagnostic criteria, or in medical therapeutical monitorization, alternative that lately has become very important. In the present study 33 patients are included, in two groups. Group I women with uterine leiomyomatosis (n = 17) and Group II (n = 16) without UL. A prospective, double blind, transversal of cases and control study. Connective tissue concentration was evaluated based on collagen determination. The evaluation of muscular tissue was done by desoxyribonucleic acid (DNA) measurement. The results showed a significant increase in connective tissue concentration (until 500%) and a significant diminution of cellularity (DNA) in women with UL, as compared with control group. The main biochemical and clinical implications of these findings, are commented upon.

Adult↗

PubMed1992

[Laparoscopy-hysteroscopy at the National Institute of Perinatology].

Seventy five patients were studied. They underwent diagnostic laparoscopy-hysteroscopy. All of them had hysterography. This study was conducted at Biology of Reproduction Department of Instituto Nacional de Perinatología. Laparoscopy-hysteroscopy showed better results to obtain diagnostic and therapeutic information, than the other methods separately without significately increase in surgery time and without complications.

Adult↗

PubMed1992

[Presentation of a mathematics formula of duplicated times of estradiol predictive for ovular harvesting].

30 patients were studied, that were included in the IVF program of the INPer. The estradiol response was studied and was correlated with the number of retrieved oocytes. The previously known E2 values considered as indicative for cancellation did no were observed in this series, and there are proposed new ones, also prognostic criterion for oocyte retrieval are proposed.

Estradiol↗

PubMed1992

[Multifactorial analysis of the blood levels of LH, FSH and estradiol in relation to ovular harvesting rates, fertilization and segmentation in patients undergoing assisted reproduction (GIFT-FIVTE)].

This study shows that there is certain tendency to asssign more value to the observation of follicular growth by ultrasound than to hormonal levels "per se". However, the appreciation of growth is only part of the phenomenon of development and ovarian maturity, for that, surveillance with hormonal monitor of ovarian response keeps with a most important role in Assisted Reproduction Clinica. The basal levels, mainly of FSH and in a less degree LH, inversely correlate with the amount of retrieved ovocytes. Estradiol values should be interpreted with a fixed point of reference, as the day of HCG administration, and a direct relation is seen between estradiol levels and captured ovocytes; however, is of highest usefulness to value the conduct of estradiol level, with the knowledge that the prognosis for good capture rates improves with ascending values and above 700 pg in the day of HCG administration.

Cleavage Stage, Ovum↗

PubMed1985