Biomedical subjects

A Alves Júnior

Publications and source records attributed to A Alves Júnior.

8 recordsLinked to original sources

PubMedDate not supplied

[Grynfelt's hernia. A case report and review of the literature].

Lumbar hernias are rare lesions. They involve the extrusion of visceral contents through a defect in the posterolateral abdominal wall. Only 250 a 300 cases had been reported in the literature. They occur most often in the superior lumbar triangle (Grynfelt's hernia). All lumbar hernias must be treated with surgery and the preferable surgical approach is done retroperitoneally. Primary repair, autologous tissue or prosthetic material may be used to obliterate the defect. The authors report a case of Grynfelt's hernia in which polypropylene mesch was placed pre-peritonially.

Female↗

PubMedDate not supplied

[Villous adenoma of the Vater's ampulla].

Benign tumors of the ampulla of Vater are rare. The villous adenoma, the most common benign tumor of this region, has a high tendency to malignant transformation. Postmortem studies showed an incidence of 0.04-0.12% adenomatous lesions of the papilla of Vater. The authors present a case of villous adenoma of the ampulla of Vater and make a review of the literature.

Adenoma, Villous↗

PubMedDate not supplied

[Mesenteric cyst].

Mesenteric cysts are rare abdominal tumors. Their incidence varies in different papers from one in 27,000 to one in 250,000 hospital admissions. Five patients with mesenteric cysts were treated at Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo between November 1982 and October 1992. The most common location was in the small bowel (60%). All of them were treated by surgery. One case was found incidentally. Treatment of choice is enucleation. It was realized in two cases (40%). The others had segmental bowel resection.

Abdominal Pain↗

PubMedDate not supplied

[Splenic cyst. Review of the literature and report of 2 cases].

Splenic cysts are rare lesions. By 1978, only 651 cases had been reported. Over the years, the management of splenic cysts has changed with advances in surgical techniques. The traditional treatment of these lesions has been splenectomy. The recognition of the post splenectomy complications has led to emphasis on conservation of splenic tissue. Nowadays, the tendency is to use splenic salvage techniques: partial splenectomy, partial splenic decapsulation and laparoscopic assistance. The purpose of this paper is to review the literature, and to report two cases of splenic cysts that were treated by the conservative method.

Adult↗

PubMedDate not supplied

[Lung lesion in acute pancreatitis].

Clinically detectable signs of lung injury develop in up to 70 percent of patients with acute pancreatitis. In order to study the pulmonary injury, experimental haemorrhagic pancreatitis was induced in 63 Wistar rats by intraductal injection of 5 per cent sodium taurocholate. Investigations were carried out 2, 4, 6, 12, 24 and 48 hours after the end of pancreatitis induction. Lung injury was maximal at 12 hours after pancreatitis induction, pancreatic enzymes (amylase and trypsin) in peritonial fluid were maximal early (2-4h) and serum levels were maximal at about 4 hours after induction. In conclusion, in experimental acute pancreatitis pulmonary injury occurs 12 h after the start of infusion with increase in vascular permeability of the lung. This lesion may be related to pancreatic enzymes in peritonial fluid and blood.

Acute Disease↗

PubMedDate not supplied

[Lung injury in acute pancreatitis. Influence of pancreatic enzymes reduction].

UNLABELLED: A previous report has show that cerulein in physiological doses reduces the rate mortality of pancreatitis by decreasing the enzyme content of the pancreas. Clinically detectable signs of lung injury develop in up to 50-70 percent of patients with acute pancreatitis. The aim of the present study was to assess the effect of acute reduction of pancreatic enzyme content on the pancreatitis pulmonary injury. Experimental haemorrhagic pancreatitis was induced by intraductal injection of 5 per cent sodium taurocholate in two groups of Wistar rats: group I (pancreatitis) and group II (pancreatitis after decreasing pancreatic enzyme content). Dye Evans blue was used to evaluate the lung injury. The degree of histologically observed lesions were similar in both groups, but the pulmonary lesion was smaller in group II than group I (p < 0.05). IN CONCLUSION: 1) pancreatitis' pulmonary lesion may be related with pancreatic enzymes that reach the blood stream and 2) the reduction of the pancreatic enzyme content has a beneficial effect on acute pancreatitis and reduces its pulmonary injury.

Acute Disease↗

PubMedDate not supplied

[Protective effect of reduction of pancreatic enzyme content on the pulmonary disease induced by acute pancreatitis].

Lung injury develop in up to 50-70 percent of patients with acute pancreatitis. Cerulein in physiological doses reduces the rate mortality of pancreatitis by decreasing the enzyme content of the pancreas. In order to assess the effect of acute reduction of pancreatic enzyme content on the pancreatitis pulmonary injury, pancreatitis was induced in Wistar rats by intraductal injection of 5 per cent sodium taurocholate: group I, with pancreatitis; group II, pancreatitis after decreasing pancreatic enzyme content; group III, control group. Dye Evans blue was used to evaluate the lung injury. The pancreatitis pulmonary injury was smaller in group II than group I (P < 0.05) but it was similar to control group (group III). In conclusion, it is speculated that the reduction of the pancreatic enzyme content reduces the pancreatitis pulmonary injury by decreasing the quantity of pancreatic enzymes reaching the systemic circulation.

Acute Disease↗

PubMedDate not supplied

[Physiopathology of lung injury in acute pancreatitis].

Clinically detectable signs of lung injury develop in up to 50-70 percent of patients with acute pancreatitis. Despite that, the physiopathology of the lung injury associated with acute pancreatitis is unclear so far. Pulmonary edema is the main respiratory complication in acute pancreatitis. Increased permeabilities of the pulmonary endothelial and alveolar epithelial barriers are the causes of the pulmonary edema. Several factors have been regarded as the cause to pulmonary edema: release of pancreatic-derived proteolytic enzymes, oxygen-free radicals, phospholipase A2, free fat acids, tumor necrosis factor, platelet activating factor, arachidonic acid metabolites and pulmonary embolization. Understanding lung injury physiopathology enables physicians to a better therapeutic approach of the patients with acute pancreatitis. The aim of this paper is to expose the theories that explain the pancreatic-derived lung injury.

Acute Disease↗