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A Amanullah

Publications and source records attributed to A Amanullah.

23 records · Page 2Linked to original sources
PubMed1992

Early exercise thallium-201 single photon emission computed tomography in unstable angina: a prospective study.

To evaluate the safety and diagnostic value of early symptom-limited exercise electrocardiography (ECG) and exercise thallium-201 single photon emission computed tomography (SPECT) in unstable angina (UA), 39 patients were studied prospectively soon after stabilization on medical treatment. No patient had a history of myocardial infarction (MI) or revascularization and patients with left bundle branch block were excluded. Exercise ECG and exercise thallium-201 SPECT were performed 8 +/- 4 days and 11 +/- 6 days respectively after admission to hospital. Seventeen out of 39 patients (44%) had positive exercise ECGs and 22 (56%) negative or inconclusive ones. Exercise thallium-201 SPECT was positive in 26 patients (67%) and negative in 13 patients (33%). Thirty-one patients underwent coronary arteriography and 24 of them proved to have significant coronary artery disease (CAD). The sensitivity, specificity and positive predictive value of exercise ECG in detecting CAD are 62%, 86%, and 94% respectively while the corresponding results are 96%, 100%, and 100% for exercise thallium-201 SPECT. Therefore, it is concluded that the early symptom-limited exercise test is safe in medically stabilized patients with UA. Early exercise thallium-201 SPECT is highly sensitive and predictive of the presence of significant CAD among patients in the early recovery phase of UA and can be used in selecting this group of patients for coronary angiography and other therapeutic strategies.

Adult↗
PubMed1981

High performance liquid chromatography of hemoglobins: factors affecting resolution.

We have investigated the effect of various factors on resolution of hemoglobin mixtures by ion exchange HPLC. Small changes in the pH of start buffer had a considerable effect on the ability to separate HBs A2 and S. Complete separation of Hbs A2, S, A, Hb A1 fraction and Hb F required 30 min. gradient elution programs. Aging of the hemolysate obscured the presence of small amounts of Hb F. Deterioration in column performance was attributed to dissolution of some of the column packing material as well as irreversible binding of hemoglobin component(s) to the ion exchanger. Substantial differences in elution time were observed between different columns requiring modifications in the gradient programs with some columns. The resolution achieved makes the HPLC technique a powerful new tool for hemoglobin analysis.

Adult↗
PubMed1976

Neonatal jaundice.

This article discusses the production, transport, and excretion of bilirubin in the newborn period. The causes, significance, and treatment of unconjugated and conjugated hyperbilirubinemia are different; and because this is so, it is important to review the main causes and management of unconjugated hyperbilirubinemia. Conjugated hyperbilirubinemia in the newborn period could be either due to hepatocellular dysfunction or extrahepatic biliary obstruction. There are several recent advances in early differentiation and management of these two entities.

Adult↗
PubMedDate not supplied

Fetal schistocytic hemolytic anemia and umbilical vein varix.

A rare case of schistocytic hemolytic anemia presenting in a fetus secondary to a varix of the intra-abdominal umbilical vein is reported. A patient was referred to our hospital at 32 weeks of gestation because of an abnormal hypoechoic finding in the fetal liver. Prenatal ultrasound showed turbulent flow through a 12-mm diameter dilatation of the fetal intra-abdominal umbilical vein consistent with a varix. Cardiomegaly also was noted. At birth, the 1098-g, growth-retarded, male neonate was in severe congestive heart failure secondary to anemia as the initial hemoglobin was 5 g/dL. Additional evaluation found the anemia to be secondary to schistocytic hemolysis. After the neonate received a transfusion of packed erythrocytes and supportive care, the anemia quickly resolved, and he was discharged to home doing well after a 6-week stay in the neonatal intensive care unit. Prompt recognition of the varix prenatally and thorough evaluation of the newborn postnatally led to appropriate diagnosis and treatment.

Adult↗