[Combined long-term (24 hours) esophagogastric pH measurement in studying scleroderma patients].
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Biomedical subjects
Publications and source records attributed to A Ambrosio.
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A clinical trial using iopamidol, a non-ionic contrast medium, in various iodine concentrations (300, 200 and 150 mg I/ml), was carried out in 947 children, aged between 1 day and 14 years, who underwent various neuroradiologic procedures: computed tomography (CT) cisternography (n = 307), CT ventriculography (n = 203), CT myelography (n = 153), and conventional myelography (n = 284). No significant variation in vital signs and neurologic status was recorded during and up to 72 hours after the examination. Psychic agitation was the major effect registered, being clearly related to the type of procedure used. A significant reduction of untoward side effects (about 50%) was observed using the lower concentrations of the medium. Iopamidol 150 mg and 200 mg represented the optimal concentration for CT enhancement, these concentrations reducing artifacts; the 300 mg I/ml concentration gave best results in conventional radiology. It seems that the lower concentrations of iopamidol (200 and 150 mg I/ml) can be usefully employed in pediatric neuroradiology, with preserved contrast and dramatically reduced untoward reactions.
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This paper analyzes our findings in a series of 1900 CT examinations carried out on 950 children after ventricular drainage. Blood in the ventricles is a relatively frequent findings in the immediate postoperative course, and gliotic or poroencephalic phenomena are often found in the late course. Persistence of ventricular dilatation and periventricular lucency has been observed several times. Extracerebral collections and septic complications are not rare findings, but trapped fourth ventricle and choroidal-ependymal reactions are only rarely observed.
Computed tomography has proved very valuable in the diagnosis of central nervous system changes in tuberous sclerosis. A full analysis of the CT findings in 34 cases is presented. Intracranial calcifications--periventricular, corticosubcortical, within the white substance or in the posterior cranial fossa--were the most frequent finding, followed by parenchymal hypodensities and tumors. Hydrocephalus and atrophy, focal or diffuse, were rare.
The diagnostic features of CT images of the spine are constantly influenced by some limitations of the method because of the peculiar configuration of the human spine. Recent generations of CT scanners greatly improve the results but with the second generation (Acta 0200 FS Pfizer Scanner) we have been able to develop a modified scan reconstruction method to maintain the quality of our spinal images, thanks to the very flexible software of our CT scanner.
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Extracranial congenital arteriovenous malformations are often associated with dural and/or cerebral malformations. One case is presented. The angiography of the common carotid artery revealed no evidence of abnormal vessels into the internal or external carotid territory. The injection of contrast medium into an enlarged epicranial vein showed the extracranial malformation, well opacified; the phlebography revealed also a small dural malformation draining in the superior sagittal sinus. The Authors outline the importance of complete angiographic study in all the cases of extracranial vascular malformations even if the carotid angiography is apparently normal.