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Biomedical subjects

A Anggård

Publications and source records attributed to A Anggård.

8 recordsLinked to original sources
PubMed1979

Results of the treatment of achalasia by pneumatic dilatation.

Thirty-three patients treated at the Karolinska Hospital for achalasia of the esophagus during the period 1968--78 have been reexamined. Twenty-eight of these patients underwent pneumatic dilatation. Excellent and good results were obtained in 79% of cases; in 21% the result was considered poor. In 2 cases the esophagus was perforated during dilatation--a perforation rate of 5% of the total number of dilatations. In 6 cases the lower sphincteric pressure was calculated before and after dilatation. It was found to be higher than normal, preoperatively, but reduced to a near-normal value postoperatively.

Adolescent↗
PubMed1979

Vasomotor rhinitis--pathophysiological aspects.

Vasomotor rhinitis is commonly defined as an unspecific hyperractivity of the nasal mucosa. The symptoms might be due to increased parasympathetic activity to the nose with the release of vaso-secretory active substances. Experimental data from the cat suggest that the postganglionic parasympathetic mediator of nasal secretion is cholinergic, whereas the vascular responses appears to be due to a different mechanism. Apart from a rich sympathetic and parasympathetic innervation of the nasal mucosa there are other nerve fibres containing substance-P (SP) and vasoactive intestinal polypeptide (VIP). The secreto-vasomotor responses can be influenced by activation of these fibres and the atropine resistant vasodilatation seen following Vidian nerve stimulation thus may partly be due to activation and release of SP and VIP. Furthermore, other vasoactive substances released such as e.g. SRS or Kallikrein may participate in these reactions.

Animals↗
PubMed1975

Parasympathetic control of blood circulation and secretion in the nasal mucosa.

The effects of selective parasympathetic nerve activation on the secretory response and the vascular exchange and capacitance sections in the cat nasal mucosa were studied. The vascular events were investigated by measuring the local disappearnce of 125I- and changes in gross pulse rate from 131I- labelled serum albumin as monitored over the nose. A frequency-dependent increase in nasal secretion and local blood content occurred in the range 0.5-12 imp/sec: an increase in disappearance rate was observed at the same time. This indicates that the vascular and secretory responses are activated simultaneously. The secretory responses, but not the vascular events, were shown to be blocked by atropine. The results thus shown that the postganglionic parasympathetic mediator of nasal secretion is cholinergic, whereas the vasodilatation appears to be due to a different mechanism, which is not sensitieve to atropine. The beneficial effect of some antihistamines in vasomotor rhinitis may thus be due to their anticholinergic properties.

Animals↗
PubMedDate not supplied

Parasympathetic influence on the nasal mucosa.

The effect of graded parasympathetic nerve stimulation on the exchange and capacitance vessels of the nasal mucosa, as well as the secretory response, is reported. Possible postganglionic mediators of the vascular and secretory effects are discussed.

Atropine↗