Biomedical subjects
Publications and source records attributed to A Antal.
We have performed the first laparoscopic appendectomy in Hungary. Laparoscopic appendectomy is a new, minimally invasive method in abdominal surgery. We consider it a worthwhile alternative to classical appendectomy.
The left somatosensory cortex of PVG/C rats was subjected to a transcranial cold lesion, spontaneous and evoked cortical activity was studied 2-3 weeks after the lesion. The spontaneous activity underwent a depression at the focus of the lesion. Close to the epicentre of the lesion, the amplitude of the potentials evoked by electrical stimulation of the contralateral whisker pad was considerably smaller than in the controls and an almost complete reduction of the initial positive phase was found. Perifocally, 3-4 mm from the epicentre, evoked potentials with enhanced amplitudes were recorded in all experiments. It seems that considerable damage took place at the epicentre of the lesion, while perifocally an excitatory (and/or inhibitory?) mechanism was activated.
The smooth muscle responses to electric stimulation of intact, slightly or severely inflamed, isolated human appendix strips were studied. No changes were noted in the motility of the not inflamed and slightly inflamed appendices, (simple appendicitis), the preparations responded to nervous stimulation with contractions of the same size. The smooth muscle contractions were blocked by atropine, and enhanced by physostigmine, which proves the cholinergic nature of the innervation. The severe inflammation (acute phlegmonous appendicitis) reduced also the contraction and relaxation of the appendix strips. With the advancement of the inflammatory process, the decreased motility of the appendix can play an in vivo role in the rapid progress of the process.
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This study contains a brief review of the changes in the technique of laparoscopic appendectomy. The authors' experiences with the methods they applied are reported. The authors emphasize on the benefits of laparoscopic appendectomy as opposed to traditional appendectomy, and advocate its wide-range application.
The postoperative complaints of patients having been subjected to laparoscopic cholecystectomy have been studied. Residual gallstones involving clinical symptoms have not been observed. Right subcostal pain, meteorism, and nausea due to faulty diet showed a slight difference in favour of the laparoscopic method when compared to traditional surgery. The laparoscopic method was qualified as excellent by over 95 per cent of the patients.
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