[Antimicrobial prophylaxis in cataract surgery].
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Anti-Infective Agents↗
Biomedical subjects
A Arias Puente
Publications and source records attributed to A Arias Puente.
[Digital analysis of the optic disc with fundus camera: a study of variability].
PURPOSE: To determine the variability of the measurements of the optic discs applying digital analysis techniques and working with a digital camera available for clinical use. METHOD: We used a fundus camera with telecentric optic system (Zeiss FF 450 IR plus) and a 3 CCD high resolution colour video camera. We used a digital analysis system (Visupac 3.2.1) equipped with measurement systems. The images were studied by three observers with different degrees of experience who analysed the optic disc diameters (horizontal and vertical) and the total optic disc area. 180 measurements were made. RESULTS: The coefficient of total variability for the studied parameters presented a range from 1.04 to 2.08%. The variability attributable to the observer was found to be lower in the case of the observer with a higher imaging analysis experience, with a range from 0.42 to 1.17% for the lineal measurements (vertical and horizontal diameters) and from 0.60 to 2.11% for measurements of the area (total optic disc area). CONCLUSIONS: The digital analysis of optic disc images obtained with conventional fundus cameras, equipped with telecentric optic systems, allows reproducible measures and can be easily employed in clinical practice.
Analog-Digital Conversion↗
[Efficiency of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers].
PURPOSE: To evaluate the clinical efficiency and tolerability of brimonidine and dorzolamide twice daily as an adjunctive therapy for glaucoma patients with an inadequate response to beta-blockers therapy. METHODS: This multicenter prospective analysis included 92 patients (180 eyes) with primary open-angle glaucoma or ocular hypertension on therapy beta-blockers and with intraocular pressure (IOP) greater than or equal to 18mmHg. The patients were randomly treated either with brimonidine 0.2% or dorzolamide 2% added for three months. Efficiency was determined by the reduction in 15% IOP from baseline at the first and the third month. RESULTS: Mean pre-treatment IOP was 22.37 DE 2.8 mmHg in the brimonidine group and 22.38 DE 2.6 mmHg in the dorzolamide group; mean post-treatment IOP decrease was 4.39 mmHg in the brimonidine group and 3.29 mmHg in the dorzolamide group. Clinical control at the first month was achieved in 78.3% and 71% of cases respectively (p=0.05). No statistical differences existed between groups for systemic adverse events. Four patients on brimonidine discontinued treatment due to local side effects. In the dorzolamide group, two patients left the treatment referring itching and three others left due to ocular allergy. CONCLUSIONS: This study found similar efficiency and safety when treating with brimonidine or dorzolamide as an adjunctive therapy for patients with hypertension or primary open-angle glaucoma.
Adrenergic beta-Antagonists↗
[Indocyanine green angiography in chorioretinal inflammatory diseases].
PURPOSE: To determine the role of indocyanine green angiography (ICG) in handling chorioretinal inflammatory disorders. METHOD: We present several posterior uveitis whose diagnosis and therapeutic approach was facilitated with ICG. RESULTS: ICG is useful in the differential diagnosis of < >. In serpiginous choroiditis, the edges and the progression of the inflammatory areas are clearly delineated. In infectious uveitis such as toxoplasmosis, ICG determines the presence or absence of active lesions. There are granulomatous diseases such as sarcoidosis where some areas of choroidal inflammation that cannot be detected with other methods are shown by ICG. Moreover, ICG can detect areas of subretinal neovascularization in some choroidal pathologies such as polypoidal choroidal vasculopathy. CONCLUSIONS: ICG appears to be a useful and complementary tool in the clinical interpretation of posterior uveitis.
Adult↗