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Biomedical subjects

A Arif

Publications and source records attributed to A Arif.

13 recordsLinked to original sources
PubMed2002

Juvenile hormone stimulated tyrosine kinase-mediated protein phosphorylation in the CNS of the silk worm, Bombyx mori.

In vitro studies with the larval CNS of the silkworm, Bombyx mori revealed the phosphorylation of a 48-kDa protein, which was not dependent on cyclic nucleotides. Studies also revealed modest phosphorylation of this protein by a calcium-dependent but calmodulin-independent mechanism. However, phosphorylation of this protein was greatly enhanced in the presence of juvenile hormone (JH) I by a calcium-independent mechanism. This stimulatory effect of JH was seen in both homogenates as well as in intact CNS of Bombyx. Immunoblotting studies revealed the cross-reaction of this 48-kDa protein with phosphotyrosine monoclonal antibody and the phosphorylation of this protein was inhibited by genistein. This study suggests that the 48-kDa protein is a substrate for tyrosine kinase. The phosphorylation of this protein was also observed in other larval tissues such as salivary gland, fat body, and epidermis of Bombyx.

Animals↗
PubMed1991

Complications of caustic ingestion.

The use of steroid and antibiotic prophylaxis no longer is tenable on the basis of recent studies showing their inability to favorably influence the outcome of caustic injuries. The need for early endoscopic and radiologic assessment if not gastroesophagectomy for severe injuries now is the management of choice. Further efforts to identify high-risk populations and efforts to educate them of the dangers must continue.

Adult↗
PubMed1988

Drug abuse and prevention programs in 29 countries.

In this paper, drug prevention programs in 29 countries are reviewed and summarized. The material was gathered from the reports that each country had prepared for the World Health Organization project on Guidelines for Drug Abuse Prevention. Each report provided a detailed schedule of background data on drug abuse and prevention programs in that country. The sophistication of prevention programs varies considerably from one country to another and depends on the degree and nature of the problem. An analysis of this material indicates that the seriousness of the drug problem is well recognized in some countries but not in others. In some of the latter countries it is obvious that no real problem exists, while in others little is known about the extent of the problem and little effort is spent in this area.

Cross-Cultural Comparison↗
PubMed1981

Nomenclature and classification of drug- and alcohol-related problems: a WHO Memorandum.

Earlier work in this field is reviewed and present concepts and terminologies are examined in detail. A revised way of dealing with ideas implicit in the terms "drug abuse" or "drug misuse" is proposed; the term "neuroadaptive state" is suggested as an alternative to "physical dependence"; a profile is given of the elements that constitute a "drug dependence syndrome"; and the need to differentiate conceptually between "dependence" and "drug related disability" is stressed. A model of dependence is outlined in which dependence is considered as a psycho-physiological-social syndrome determined and kept going by a complex system of reinforcements. The association between substance use and mental illness is discussed with emphasis on possible two-way relationships. The need for population studies and in particular for longitudinal studies is emphasized. The bearing of all the fore-going considerations on work towards the revision of relevant classification systems is considered, and, in the final section, several recommendations on nomenclature are brought together and suggestions are made for research that might lead to refinement of classification and diagnostic systems.

Alcoholism↗
PubMedDate not supplied

A study of aplastic anemia at the Department of Child Health, School of Medicine University of North Sumatera/Dr. Pirngadi Hospital, Medan.

A study of aplastic anemia in children in a period of June 1980 to June 1989 was done to evaluate the pattern of aplastic anemia in children. The cases consisted of 55 children, 30 males (54.55%) and 25 females (45.45%). Most of the patients (47.27%) were found in the age group of 10 to 15 years. The complaints were paleness (90.91%), fever (56.45%) and bleeding (52.72%). The hemoglobin concentration was 4.25 +/- 1.17 g/dl (mean +/- SD), and the thrombocytopenia was generally severe. Prednisone or combination of prednisone and oxymethalone was given in addition to blood transfusions, antibiotics and vitamins. The outcome was difficult to evaluate because of the irregularity of treatments. Of the 55 children, 9 (18.02%) contracted leukemia after 1-5 months.

Adolescent↗