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Biomedical subjects

A Arikan

Publications and source records attributed to A Arikan.

7 recordsLinked to original sources
PubMed1992

Effects of nickel-chrome dental alloys used in dentistry on saliva and serum nickel levels, peripheral T-lymphocytes and some other blood parameters.

Epidemiological investigations have shown that nickel is a potent sensitivity producing agent. However, it is not known if intra-oral use of nickel-chrome alloys can cause any sensitization reaction. The purpose of this study was to determine if nickel-chrome alloys used in dentistry influence nickel levels in saliva and serum and whether there were associated changes of some blood parameters such as lymphocyte, T-lymphocyte, neutrophil, eosinophil, basophil and monocyte. The study was performed on 10 patients all of whom had no medical and dental history of using nickel containing drugs or restorations. Four unit fixed partial prostheses containing 22.97% nickel and 22.65% chrome were constructed and worn by the patients. Blood and unstimulated whole saliva samples were taken from the patients before insertion of the prostheses and then 1 month and 6 months post-insertion. Hematocrit determinations, total and differential leucocyte count, total T-lymphocyte counts and serum nickel concentrations were determined from the blood samples and salivary nickel concentrations from the saliva samples. It was found that there were no significant changes in circulating T-lymphocyte and monocyte population but a decrease was found in circulating eosinophil and an increase in circulating neutrophil and basophil populations.

Adult↗
PubMed1992

A study of chromium, nickel and cobalt hypersensitivity.

Hypersensitivity reactions to chromium, nickel and cobalt were investigated in the preclinical, fourth year and fifth year students of the Dentistry Faculty of Marmara University, Türkiye. A Standard patch test was performed. Four patches were applied to the shoulder blades of the students. Three of them contained small amounts of 0.5% potassium chromate, 5% nickel sulphate and 1% cobalt chloride respectively. The fourth (control) patch was of petroleum jelly. Questionnaires were used to determine sex and history of any previous allergy to jewelry. After 48 hours, the patches were removed and results assessed. For each base metal, no statistically significant difference was found in the incidence of hypersensitivity reaction between the groups. Nor was there a significant difference in response found between metals, for all of the students tested. Although women were found to have a higher rate of nickel hypersensitivity than men, no such sex difference was found chromium and cobalt. No significant relationship was found between a history of allergy to jewelry and chromium hypersensitivity, however there was a significant difference for nickel and cobalt hypersensitivity. In confirmation of our tests, significant relationships were found between previous allergy histories and the respective patch test results.

Chromium↗
PubMed1991

Management of suppuration in regional lymph nodes secondary to BCG vaccination.

We describe 50 patients with suppurative regional lymphadenitis following intradermal BCG vaccination. For non-drained suppurations we performed needle aspiration in twenty-three patients (aspiration group). Of the remaining 27 patients (drainage group) 16 had spontaneous drainage and 11 incisional drainage. In the drainage group, 17 patients were followed up conservatively. Ten patients from the drainage group and 3 patients from the aspiration group (drained after needle aspiration) accepted total surgical excision to terminate the drainage. Twenty of twenty-three patients in the aspiration group recovered after needle aspiration. Average period of cessation of drainage and healing of wound was 7.5 weeks in patients with drainage (spontaneous and incisional). Healing was complete after total surgical excision of draining suppurations in all of 11 patients. We concluded that simple needle aspiration was sufficient for the treatment of suppurating but non-drained BCG lymphadenitis. For suppurating lymph nodes that were surgically (not recommended) or spontaneously drained, a more invasive procedure, total surgical excision, was proposed to terminate the long and disturbing drainage period.

BCG Vaccine↗
PubMedDate not supplied

Ectopic thoracic kidney.

A five-month-old female infant was hospitalized for bronchopneumonia. Ultrasonography and other studies demonstrated the presence of an ectopic thoracic kidney with normal anatomical structures.

Female↗