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Biomedical subjects

A Aroński

Publications and source records attributed to A Aroński.

At least 19 recordsLinked to original sources

[The use of dopamin in shock and heart failure (author's transl)].

The action of dopamine was evaluated in 18 patients with cardiogenic shock after myocardial infarction, in 14 patients with heart failure and in 18 patients with low-output syndrome after cardiac surgery. In the patients with shock, dopamine increased significantly systolic arterial blood pressure, myocardial contractility, diuresis and sodium excretion. In patients with heart failure a great increase in diuresis and sodium excretion with decrease of CVP was observed. In patients after cardiac surgery dopamine produced a significant increase of arterial blood pressure and diuresis with decrease of CVP. The clinical application of dopamine and the advantages of the use of dopamine combined with other catecholamines were discussed.

Blood Pressure↗

Monitoring pulmonary artery pressures in critically ill patients.

A flow-directed Swan-Ganz catheter was used for the catheterisation of the pulmonary artery in critically ill patients. The monitoring of pulmonary artery pressures provided reliable information regarding left ventricular function and pulmonary vascular resistance. Moreover, the pulmonary artery catheter can be used for mixed venous blood sampling. Experiences with pulmonary pressure monitoring for the assessment of left ventricular performance in patients with myocardial infarction and left ventricular failure, for the estimation of lung function in patients with respiratory failure and for the selection of the optimal level of positive end-expiratory ventilation are presented. The advantages of pulmonary artery pressure monitoring for the assessment of the circulatory and respiratory status of critically ill patients are stressed, and technical problems and complications are discussed.

Blood Pressure↗

[A study on the action of naloxone (author's transl)].

The action of naloxone was evaluated in two separate investigations. In the first study the action of naloxone, nalorphine and placebo was compared in 5 healthy volunteers using a double-blind, cross-over trial. After the administration of nalorphine changes in psychical state and respiratory depression were observed in all subjects, whereas naloxone caused no changes even after very high doses. It is concluded, that naloxone has no agonism or intrinsic narcotic activity as opposed to nalorphine. In the second investigation, the efficacy of naloxone in antagonising large doses of fentanyl was evaluated in 25 surgical patients. The administration of naloxone caused a significant increase of respiratory rate and minute volume, a decrease of arteriell pCO2 and an increase of pO2. The results obtained confirmed that naloxone has a fast and potent anti-narcotic action.

Adult↗