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Biomedical subjects

A Arora

Publications and source records attributed to A Arora.

146 records · Page 9Linked to original sources

Gastrointestinal tract infection in immunocompromised hosts.

The recent regognition of AIDS has stimulated the development of newer cytotoxic therapies and hematological support system which have prolonged the life of these immunocompromised subjects. Moreover, greater number of patients are being recognised who are susceptible to various opportunistic infections involving the GI tract. In view of the poor anti-inflammatory response and minimal signs and symptoms of infection, the diagnosis of these organisms is often difficult. Hence a proper knowledge of the predisposing conditions and meticulous attention to minor symptoms and thorough physical examination alone can lead to an early diagnosis of infection. The common infectious agents include cryptosporiodium, herps virus cytomegalovirus and Giardia. Since, a satisfactory treatment is not available for many of these pathogens, attention should be paid to preventive measures while injudicious use of broadspectrum antibiotics must be checked to prevent superinfections.

Acquired Immunodeficiency Syndrome↗

Massive lower gastrointestinal bleeding as a presenting feature of Behcet's disease.

This reports a 27 yr old female Patient with seronegative polyarthritis who presented with lower GI bleeding and subsequently developed evidence of cutaneous vasculitis (palpable purpura) and orogenital ulcers. The cause of the GI bleeding was multiple ulcerations in the terminal ileum, cecum ascending colon and transverse colon. Continued and massive bleeding necessitated surgical resection of the involved segment of gut which on histopathological examination confirmed the presence of vasculities. This patient was thus diagnosed as having Behcet's disease. Although major GI bleeding is a rare manifestation of Behcet's disease with vasculitis of the gut, one must consider this possibility if the patient has multi-system involvement with evidence of vasculitis involving the skin in the form of palpable purpura.

Adult↗