[Intra-artoc balloon pump in the treatment of low minute/volume during heart surgery].
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Biomedical subjects
Publications and source records attributed to A Arvay.
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Anoxemic changes of the myocardium were examined at 20 patients operated on in extracorporal circulation. At a mild degree hypothermia (30 degrees C) morphological changes appear after a 20 minutes period of anoxaemia. Damage to the myocard of irreversible character could be revealed after an anoxaemic period of 43--55 minutes. An intermitting perfusion of the coronary arteries delayes the formation of the lesions, although in cases of ligation of the aorta for 90 minutes severe mitochondrial changes and deformation of cells were seen. The best method for protecting the myocard is an isotherm perfusion of the coronary arteries. Clinical and laboratory findings show that necrosis of the myocard has a focal character and may play a part in formation of postoperative lesions.
The changes induced in the lungs have been studied, in the course of 15 heart operations with extracorporeal circulation. In each case material was obtained from lungs after the thoracotomy, before starting the perfusion and after its termination. The pulmonary structure showed changes against the control material already prior to perfusion, the most conspicuous alternations of the capillary endothelial cells and of the basal membrane. Examination of the surfactant by ruthenium red demonstrated changes in the reaction; from this circumstance the conclusion has been drawn that affection of the surfactant may have a part in the postperfusion syndrome.
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