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A Audebert

Publications and source records attributed to A Audebert.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

Changes in haemostasis after laparoscopic surgery in gynaecology: contribution of the thrombin generation test.

Surgery induces immediate hypercoagulability by direct alteration of the vascular bed, release of procoagulant substances from the extravascular spaces and blood flow decrease, and delayed hypercoagulation in response to tissue damage which triggers inflammatory responses. Thus, the postoperative period represents a high-risk time for thrombosis. Recognition of high-risk individuals would make it possible to improve thromboembolism prevention. We studied in women undergoing laparoscopic surgery a series of markers known to be related to the thrombotic risk and confronted their results with those of a global test, the thrombin generation test (TGT) described by Hemker's group. Our results show that two groups of patients can be distinguished according to usual risk markers (PAI-1, TAT, body mass index): the higher risk group demonstrates higher initial TGT values, but also a postoperative decrease of the TGT values whose mechanisms remain to be defined.

Adult↗
PubMedDate not supplied

[Routine laparotomy in Hodgkin's disease. Remarks apropos of 50 personal cases].

The authors report fifty personal cases of routine exploratory laparotomy during Hodgkin's disease, carried out in either first or second intention. They compare the results obtained to those in other series published in the literature. The results emphasize the undoubted change in classification after laparotomy, and consequently, changes in therapeutic attitude, but also raise new problems which leave the question open.

Abdominal Neoplasms↗