Biomedical subjects

A Azumi

Publications and source records attributed to A Azumi.

21 records · Page 2Linked to original sources

PubMed1992

[Retinal circulation and ocular blood barrier in diabetic retinopathy].

Macular capillary blood flow velocity, the score of fluorescein angiography in posterior region and aqueous flare intensity were investigated in 38 diabetics (41 eyes) and 6 normal subjects (6 eyes) to clarify the relationship among retinal circulation, blood-retinal barrier and blood-aqueous barrier. Macular capillary blood flow velocity was measured by means of the blue field entoptic phenomenon, the score of fluorescein angiography was graded by the extent of edema in the posterior region, aqueous flare intensity was measured with a flare-cell meter. The results showed that the reduction of macular capillary blood flow is significantly associated with an increase in fluorescein angiography score and aqueous flare intensity via diabetic retinopathy (p less than 0.01).

Adult↗

PubMedDate not supplied

The Kobe earthquake and recurrent endogenous uveitis.

The mechanism of recurrent endogenous uveitis remains uncertain but it is generally believed to be affected by both heredity and environment. On January 17, 1995, the Hanshin-Awaji (Kobe) area of Japan experienced a major earthquake which killed more than 6300 people and forced 310,000 to take refuge in emergency shelters. All inhabitants of this area suffered severe stress due to the sudden changes in their living environment. We investigated the recurrence rate of endogenous uveitis before and after the earthquake in 116 patients who had been followed for more than 2 years (since July 17, 1993) at Kobe University Hospital. The postquake rate was significantly higher than the prequake rate (10% vs 3%); women were more often affected than men. Our data suggests that psychological stress due to the sudden changes in living conditions following the earthquake may have triggered the recurrences. It might be important to provide psychological as well as physical care for these patients after a disaster.

Adult↗

PubMedDate not supplied

Ocular ischemic syndrome in diabetic patients.

PURPOSE: Diabetes mellitus aggravates carotid occlusive disease, that can manifest as ocular ischemic syndrome (OIS). Ocular manifestations and visual prognosis of OIS in diabetic patients were retrospectively analyzed. METHODS: Twenty-three consecutive diabetic patients with OIS were divided into two groups according to the presence of iris neovascularization, and the clinical features were reviewed. RESULTS: In the first group, 14 eyes of 12 diabetic patients (11 men and 1 woman) had no iris neovascularization. Two patients had bilateral OIS. The ages in this group ranged from 50-75 years. Four eyes with optic atrophy or ischemic optic neuropathy had severe visual loss. Six eyes with hypoperfusion retinopathy or retinal vein obstruction and 2 eyes with cataract had mild visual loss. Each eye with amaurosis fugax or retinal neovascularization had no visual deterioration. Asymmetrical retinopathy was observed in 2 patients. Carotid surgery stabilized and resolved amaurosis fugax and hypoperfusion retinopathy. In the second group, 11 eyes of 11 patients had iris neovascularization. The patients were all male and their ages ranged from 53-77 years. All eyes with iris neovascularization had severe visual deterioration. In 5 patients, asymmetrical ocular manifestation was observed. Carotid reconstruction surgery and ophthalmological treatment were not successful for recovering a satisfactory visual outcome in OIS. CONCLUSION: The features of OIS in diabetic patients mimic diabetic retinopathy and manifest with asymmetrical ocular findings. Iris neovascularization is an indicator of poor visual prognosis. It is essential to recognize the early stages of OIS associated with diabetes mellitus.

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