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Biomedical subjects

A B Ackerman

Publications and source records attributed to A B Ackerman.

At least 181 records · Page 10Linked to original sources
PubMed1983

Lichen planus.

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Humans↗
PubMed1983

Lyme disease is a spirochetosis. A review of the disease and evidence for its cause.

Fourteen patients with Lyme disease showed typical clinical features of erythema chronicum migrans. Eighteen biopsy specimens in all were obtained from the cutaneous lesions of these patients. The predominant histologic finding was a superficial and deep perivascular and interstitial infiltrate composed mostly of lymphocytes, or lymphocytes and either plasma cells and eosinophils or both. The plasma cells were found most frequently in biopsy specimens taken from the peripheries of the lesions, whereas eosinophils were found mostly in the centers of lesions. With the Warthin-Starry silver stain, spirochetes were found mostly at the borders of the lesions an in biopsy specimens containing plasma cells. Spirochetes were subsequently cultured from a typical skin lesion of erythema chronicum migrans. These findings corroborate previous indirect evidence that a spirochete might be the cause of Lyme disease.

Adult↗
PubMed1983

Granulomatous mycosis fungoides. A 14-year follow-up of a case.

This is a 14-year follow-up of a patient with granulomatous mycosis fungoides. The patient has had nodular lesions of mycosis fungoides for more than 30 years, an unusually long survival for the nodular form of the disease that is often quickly fatal. The role of the granulomatous inflammatory response in his survival is speculated upon.

Follow-Up Studies↗
PubMed1982

A critique of techniques for biopsy of clinically suspected malignant melanomas.

Two hundred twenty-seven malignant melanomas, exclusive of malignant melanoma in situ, were diagnosed in the Dermatopathology Laboratory of the New York University Medical Center in a 7-month period. Of these, 143 had been suspected of being malignant melanomas by the clinicians who submitted them. These lesions had been biopsied in various ways by surgeons and dermatologists, of whom those trained more than 10 years ago were found more likely to have done scalpel excisions, whereas dermatologists trained within the past 10 years had more likely done shave or punch biopsies. All too often, dermatologists failed to perform satisfactory biopsies of lesions that they suspected to be malignant melanomas clinically.

Biopsy↗