New reactivators of phosphonylated acetylcholinesterase.
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Acetylcholinesterase↗
Biomedical subjects
A B Ash
Publications and source records attributed to A B Ash.
Hydantoins as antitumor agents.
A series of 27 hydantoins was prepared and tested as antitumor agents. These were variously substituted in the 5 position but with special emphasis on the substituents (chloro, acetyl, chloroacetyl, and methyl) in the 1 and/or 3 positions. The most active compound was 5,5-bis(4-chlorophenyl)-1,3-dichlorohydantoin with a T/C value of 190% against P-388 lymphocytic leukemia in mice.
Animals↗
Antimalarials. 1. 2-Quinolinemethanols.
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Animals↗
Antimalarials. 2. 2,6-Bis(aryl)-4-pyridinemethanols.
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Animals↗
Antimalarials. 3. 2,6-Bis(aryl)-4-pyridinemethanols with trifluoromethyl substituents.
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Animals↗
Nucleotide synthesis. I. Derivatives of thymidine containing p-nitrophenyl phosphate groups.
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Chromatography, Paper↗
Amino ketone rearrangements. VI. Synthesis of 2-alkylamino-2-phenylcyclohexanones.
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Chemistry, Organic↗