[The adult respiratory distress syndrome in eclampsia and eclamptic coma. The diagnostic problems].
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Biomedical subjects
Publications and source records attributed to A B Gruzman.
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This is an overview of counselling, medical and methodological assistance given to obstetric facilities of the Moscow region during 10 years. It is concluded that regional obstetric-gynecologic centers should be established, which incorporate an intensive care unit and a mobile resuscitation team.
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Glucose release and lactate uptake by the brain during coma is discussed. A hypothesis of autonomous gluconeogenesis in the brain is suggested. To substantiate the hypothesis use is made of the literature data on the presence in the brain of stimuli, and its provision with substrates and gluconeogenetic enzyme apparatus. Special attention is paid to the problem of gluconeogenesis energy supply during hypoxia, using proton or sodium potentials.
The article confirms an earlier discovered phenomenon that during comas and in post-coma periods the brain releases glucose and consumes lactate. It is suggested that the phenomenon is based on glucogenesis taking place in the brain from non-carbohydrate glucose precursors, which is phylogenetically predetermined and biologically expedient.
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