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Biomedical subjects

A B Nevelös

Publications and source records attributed to A B Nevelös.

12 recordsLinked to original sources

Examination of alumina ceramic components from total hip arthroplasties.

Materials analysis has been conducted on retrieved Mittelmeier-Autophor ceramic components from total hip arthroplasties, correlating articulating surface wear morphology with clinical reasons for failure. Plastically deformed, agglomerated wear debris (30-60 microns) has been identified on femoral head articulation wear surfaces, displaying exaggerated wear, especially during the initiation stage. Such surfaces were associated with clinical failures involving displacement of the acetabular cup and perforation of the cortex by the femoral stem. It is thought that this wear debris may play an important role in the promotion of the 'avalanche' wear mechanism, as it is adherent and thus difficult to remove from the wear interface.

Acetabulum↗

The three-dimensional anatomy of the proximal femur in Perthes' disease.

A new method of recording the three-dimensional anatomy of the proximal femur from a single anteroposterior radiograph is described. This technique shows that in Perthes' disease the femoral head and neck are in significant anteversion and true varus. This anatomical configuration may be important in the pathogenesis and treatment of this disorder.

Child↗

Perthes' disease. The family tree.

The discovery and use of roentgenograms by Wilhelm Röntgen in 1895 was one of the most important turning points in the history of orthopedics. Within only a few years, immense advances were made in the recognition and definition of bone and joint disorders that, until then, had been thought to be different or unusual forms of musculoskeletal tuberculosis. Perthes' disease has become one of the Lieblingsthema of orthopedics. The study of the history of Perthes' disease is fascinating: the sources of many "original" thoughts can be traced back across the world, through the years. This review begins with the 19th century, traces the emergence of the definition of Perthes' disease and some related conditions, and follows the story of the disease in the first decade of its history as a separate entity.

Femur Head Necrosis↗

The treatment of tennis elbow with triamcinolone acetonide.

Twenty-seven patients with tennis elbow were treated with triamcinolone acetonide (40 mg/ml) injected locally into the tender area without local anaesthetic. Reduction of pain or complete relief was achieved in 1 to 72 hours, although in 9 cases exacerbation of pain occurred before relief was given. The recurrence rate at 6 months was 17.8%. The study shows that triamcinolone acetonide is a useful preparation in the relief of this condition.

Adolescent↗

Osteochondritis occurring at multiple sites.

Five patients with osteochondritis juvenalis occurring at multiple sites are presented. In all cases at least one hip was affected, one child developing symptoms at the age of 8 months. Other sites included the tarsal navicular, the patella and the calcaneal apophysis. The relevance of these observations to the aetiology of coxa plana is discussed.

Child↗

Bilateral Perthes' disease.

Bilateral Perthes' disease is defined as the form of the condition where radiological changes affect both hips simulatneously. The radiological abnormalities are commonly more severe on one side than on the other. In a small proportion of patients a clear time interval exists between the onset of radiological changes in the two hips. It is suggested that this form of the condition is two unilateral and separate attacks of Perthes' disease and it is more akin to 'recurrent' Perthes' disease.

Age Factors↗

Perthes' disease: a new genetic hypothesis.

We describe the sex and age distributions of the onset of Perthes' disease in our own and six other large published series. The mathematical features of these distributions, together with the evidence for familial aggregations, agree with the theory that the disease is autoaggressive in aetiology and that two genetically-distinctive groups are at risk. We consider the frequency of affected sides - left, right, bilateral - in our own and other series: concordance for affected side(s) within sibships suggests that laterality might be genetically determined. Following Gray et al. we believe that predisposition to the disease is polygenic and we propose a simple scheme - involving an X-linked "recessive" factor and an autosomal homozygous allele in each genotype - that is reasonably consistent with the slender evidence.

Age Factors↗

Hip dysplasia without dislocation in one-year-old boys.

Six boys were examined during the second year of life, each with symptoms in one hip. The affected femoral capital epiphysis was smaller or more irregular (or both) than that of the unaffected hip but was neither subluxed nor dislocated. The subsequent radiographs revealed changes similar to those in severe Perthes' disease. Nevertheless, we give reasons for believing that this disorder in boys under two years of age should be distinguished from Perthes' disease.

Bone Diseases, Developmental↗

The treatment of congenital vertical talus.

Operative correction of congenital vertical talus in nine feet in six patients is described. The operation consists of the comprehensive lengthening of the tendons in the foot and full peritalar release without excision of the navicular; it is performed through a dorsal transverse incision.

Child↗

Rotational displacement of the lower tibial epiphysis due to trauma.

A rare form of injury to the distal tibial growth plate is described. Only two patients with such an injury have been reported previously. The injury, rotational displacement of the distal tibial epiphysis with posterior displacement of the fibula but without fracture, can be reduced easily and appears to have no lasting ill-effects.

Casts, Surgical↗

Perthes' disease. A study of radiological features.

A study is presented of the radiographs of 68 patients with unilateral Perthe's diseasemtwo types of Perthe's disease are identified: 'fragmenting' and 'non-fragmenting'. The two radiological types of the disease showed no significant differences in the age at diagnosis, the duration of symptoms before diagnosis and the duration of the disease. However, the radiologically-measureable results at healing, in terms of the epiphyseal, acetabular, acetabulum-head and comprehensive quotients were all very significantly worse when fragmentation had developed.

Age Factors↗