[Acrodermatitis enteropathica].
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Biomedical subjects
Publications and source records attributed to A B Rakhmatov.
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HLA-A, B, and C antigens were studied in 220 psoriasis patients by Terasaki and McLelland's lymphocytotoxic method. The value of relative risk for HLA-B13 and HLA-B17 antigens was estimated: 5.3 and 7.7, respectively. The detected regularities in histocompatibility antigens distribution suggest that typing of psoriasis patients may help predict, with some certainty, the course of the disease, its pattern, and clinical picture.
Routine electroencephalographic (EEG) examinations were carried out in 47 patients with psoriasis. Analysis of EEG has shown functional disorders of the brain bioelectric activity, among other things in the mesodiencephalic and stem structures. Cerebrolysin administered via various routes was used in the multiple-modality treatment of psoriasis patients. Injection of the agent into the earlobe (according to auricular acupuncture technique) has proved to be the most effective and economic.
In order to determine the basal insulinemia levels, the blood insulin levels have been radioimmunoassayed in psoriasis patients over the course of the routine glucose tolerance test. Hyperinsulinism, depending on the severity of the psoriatic process, has been revealed in 49 of the 64 examinees. Three types of insulin response to glucose load, similar to those in diabetes mellitus, have been revealed in the patients with psoriasis.
Clinical features of psoriasis have been examined in 113 elderly and senile patients. The incidence rate of complicated forms of the dermatoses, associated with manifest subjective sensations, is higher in this patient population than generally in psoriasis. Clinical and laboratory studies have revealed a number of concomitant diseases contributing to the severe course of psoriasis. Combined therapy of elderly and senile patients suffering from psoriasis included drugs normalizing metabolic processes, improving the functions of the liver, cardiovascular and nervous systems.
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