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Biomedical subjects

A B Rehman

Publications and source records attributed to A B Rehman.

4 recordsLinked to original sources
PubMed1997

Pharmacological evaluation of newly synthesized piperidinium derivatives for their analgesic activity.

Two chemically synthesized piperidinium derivatives i.e l-methyl-1-(3,4) dihydroxy phenacyl-4-hydroxy piperidinium chloride and 1-methyl-(4-p) methoxy phenacyl 4-hydroxy piperidinium bromide have been evaluated for their analgesic activity in intact albino mice by tail immersion method because of their structural similarity with opioids. Both the compounds were administered in the doses of 50 mg/kg. The results were compared with pethidine used as the reference drug. The control animal received only the vehicle. The present study suggested that both the compounds exhibit significant analgesic activity.

Journal Article↗
PubMed1977

The susceptibility of Tatera indica, Nesokia indica and Bandicota bengalensis to three anticoagulant rodenticides.

Three South-Asian rodent past species were tested for susceptibility to anticoagulant rodenticides. Wheat fluor containing 0-025% warfarin 0-0375% coumatetralyl or 0-005% difenacoum was fed to 260 Tatera indica, 140 Nesokia indica and 81 Bandicota bengalensis for 1-56 days. Tatera was about as susceptible to anticoagulants as Rattus has been reported to be. Nesokia and Bandicota were extremely variable: though the majority were highly susceptible, the slopes of the dose-mortality curves were close to zero. The difenacoum diet appeared to be more toxic than the warfarin diet to all three species, but less toxic than the coumatetralyl diet to Tatera and Nesokia. All of the anticoagulants were eventually lethal to all of the animals tested.

Animals↗